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AL Amyloidosis Clinical Trials

11 recruiting trials for AL Amyloidosis. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
11
Total Trials
11
Recruiting Now
1
Phase 3 Trials
10
Sponsors

Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT06065852

National Registry of Rare Kidney Diseases

The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research. The purpose of this research...

Sponsor: UK Kidney AssociationEnrolling: 350001 location
RECRUITINGNCT07448935

One Gene, Two Diseases: the Pathologic Role of IGLV1-44 in AL Amyloidosis and POEMS

By detailed sequence analysis and subsequent biophysical characterization of prototypic light chains, this project aims to identify sequence fingerprints in IGLV1-44 light chains...

Sponsor: Fondazione IRCCS Policlinico San Matteo di PaviaEnrolling: 1001 location
RECRUITINGPhase 2NCT06935162

Teclistamab in Previously Treated AL Amyloidosis

This is a phase II study in patients with previously treated immunoglobulin light-chain (AL) Amyloidosis to evaluate the efficacy and safety of teclistamab

Sponsor: Peking Union Medical College HospitalEnrolling: 301 location
RECRUITINGPhase 2NCT06649695

A Phase II Trial of Teclistamab in Participants With Previously Treated Immunoglobulin Light-chain (AL) Amyloidosis

This is a multicenter open-label, phase 2 study in participant with previously treated immunoglobulin light-chain (AL) Amyloidosis to evaluate the benefit of teclistamab

Sponsor: European Myeloma Network B.V.Enrolling: 3010 locations
RECRUITINGPhase 3NCT06022939

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly...

This phase III trial compares the effect of adding a stem cell transplant with melphalan after completing chemotherapy with daratumumab, cyclophosphamide, bortezomib and...

Sponsor: SWOG Cancer Research NetworkEnrolling: 33820 locations
RECRUITINGNCT04839003

A Registry of AL Amyloidosis (ReAL)

The purpose of this protocol is to generate a large registry of patients with AL amyloidosis.

Sponsor: Fondazione IRCCS Policlinico San Matteo di PaviaEnrolling: 50001 location
RECRUITINGNCT06699394

Prospective Study of Teclistamab in the Treatment of Systemic AL Amyloidosis

This study aims to evaluate the use of teclistamab in systemic AL amyloidosis and answer whether teclistamab can improve the rate of complete hematological response. This is a...

Sponsor: Peking University People's HospitalEnrolling: 202 locations
RECRUITINGPhase 1 / Phase 2NCT06569147

Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis

This study will evaluate the safety, tolerability and efficacy of elranatamab in patients with relapsed or refractory AL amyloidosis.

Sponsor: Brigham and Women's HospitalEnrolling: 491 location
RECRUITINGPhase 2NCT05898646

Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial

This phase II trial compares shorter-duration versus longer-duration maintenance therapy with daratumumab for improving survival in patients who have received initial treatment...

Sponsor: Mayo ClinicEnrolling: 962 locations
RECRUITINGPhase 1 / Phase 2NCT05451771

Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

The purpose of this study is assess safety, safest dose, and effectiveness of venetoclax in combination with dexamethasone in participants with t(11;14) positive relapsed (comes...

Sponsor: Rajshekhar Chakraborty, MDEnrolling: 534 locations
RECRUITINGNCT06855121

The Norwegian Immunotherapy in Multiple Myeloma Study

The goal of this observational study is to study the effectiveness and complications of novel immunotherapies used in the treatment of multiple myeloma in routine care in Norway....

Sponsor: St. Olavs HospitalEnrolling: 40020 locations

Frequently Asked Questions

There are currently 11 clinical trials for AL Amyloidosis, with 11 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for AL Amyloidosis, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for AL Amyloidosis, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice — always talk to your doctor about clinical trial participation.