Phase 1 Clinical Trials
Phase 1 trials test a new treatment in a small group of people (20-80) for the first time. The focus is on safety, dosage, and side effects.
About Phase 1
Phase 1 is the first step in testing a new drug or treatment in humans. Researchers evaluate safety, determine a safe dosage range, and identify side effects. These trials typically involve healthy volunteers or patients who have exhausted other treatment options.
Top Conditions
Top Sponsors
Frequently Asked Questions
Phase 1 is the first step in testing a new drug or treatment in humans. Researchers evaluate safety, determine a safe dosage range, and identify side effects. These trials typically involve healthy volunteers or patients who have exhausted other treatment options.
There are currently 1,582 Phase 1 clinical trials tracked in our database. These trials span multiple conditions and are run by a mix of pharmaceutical companies, academic institutions, and government agencies.
The conditions with the most Phase 1 trials include Ovarian Cancer (30 trials), Lung Cancer (23 trials), Systemic Lupus Erythematosus (23 trials), Breast Cancer (22 trials), Leukemia (22 trials).
To participate in a Phase 1 trial, browse the conditions below to find relevant trials, review the eligibility criteria, and talk to your doctor about whether participation is appropriate for your situation.
Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.
Source: ClinicalTrials.gov, 2026.