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Bipolar Depression Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

12 recruiting trials for Bipolar Depression. Eligibility criteria explained in plain English.

TrialFinderData lists 12 Bipolar Depression clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 3 is the largest group at 33% (2 studies); the largest phase groups are Phase 3: 2, Phase 2: 1, Phase 1: 1, Phase 1 / Phase 2: 1.

Research is led by Dr. Inge Winter (2), University of Sao Paulo (1), Mark Niciu (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Escitalopram (drug, 2 trials), followed by Sertraline, Venlafaxine.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
12
Total Trials
12
Recruiting Now
2
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT06488573

PROgram To Enhance Cardiovascular Risk Trough an Intervention of Nutrition in Bipolar Disorder

Individuals with Bipolar Disorder (BD) have twice the risk of being affected by metabolic comorbidities and a 1.8-fold increased risk of mortality from cardiovascular diseases...

Sponsor: University of Sao PauloEnrolling: 881 location
RECRUITINGNCT04480918

University of Iowa Interventional Psychiatry Service Patient Registry

The purpose of this study is to examine the effects of interventional/procedural therapies for treatment-resistant depression (TRD) and Obsessive-Compulsive Disorder (OCD). These...

Sponsor: Mark NiciuEnrolling: 10001 location
RECRUITINGNCT07108257

Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression

The goal of this clinical trial is to evaluate the safety and initial effectiveness of MR-guided focused ultrasound (MRgFUS) bilateral capsulotomy in patients with...

Sponsor: Sunnybrook Health Sciences CentreEnrolling: 101 location
RECRUITINGPhase 3NCT05973786

The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in...

Bipolar disorders affect approximately 4.5 million people across the European Union (EU) and are associated with high annual healthcare and societal costs. Bipolar disorder I and...

Sponsor: Dr. Inge WinterEnrolling: 41813 locations
RECRUITINGPhase 2NCT05296356

OSU6162 in Bipolar Depression (OBID)

An explorative, open label, single armed, flexible dose, single center, phase IIa study of 8 weeks, initiated in subjects with bipolar depression. The study will consist of 9...

Sponsor: Göteborg UniversityEnrolling: 221 location
RECRUITINGPhase 1NCT06506019

Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression

This study is an open-label, single-arm, proof-of-concept study, wherein treatment resistant bipolar depression (TRBD) participants will receive one 25 mg dose of oral psilocybin...

Sponsor: University Health Network, TorontoEnrolling: 301 location
RECRUITINGNCT07246044

HD-tDCS for Adolescent Bipolar Depression Targeting S1

This randomized, double-blind, sham-controlled clinical trial aims to evaluate the efficacy and underlying biological mechanisms of HD-tDCS targeting the primary somatosensory...

Sponsor: Jiangsu Province Nanjing Brain HospitalEnrolling: 1001 location
RECRUITINGPhase 1 / Phase 2NCT06088732

Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression

This is a 2x2, within-subjects, cross-over trial to test the anti-depressant effects of acute exercise in 20 participants with bipolar depression. Participants will complete four...

Sponsor: Laureate Institute for Brain Research, Inc.Enrolling: 201 location
RECRUITINGPhase 3NCT05603104

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a...

Schizophrenia, bipolar and major depressive disorders collectively affect over 10 million people across the EU and are associated with annual healthcare and societal costs in...

Sponsor: Dr. Inge WinterEnrolling: 12541 location
RECRUITINGPhase 4NCT06417437

Non-invasive BCI and Application Verification for Depressed People

Major Depressive Disorder (MDD) is a serious mental illness and public health problem that poses threat to both physical and mental health. According to statistics from WHO, it is...

Sponsor: Shanghai Mental Health CenterEnrolling: 4001 location
RECRUITINGNCT07021508

Efficacy and Safety Assessment of Temporal Interference Stimulation to Improve Bipolar Depression

The aim of this study was to explore the efficacy and safety of temporal interference stimulation to improve bipolar depression, as well as to explore the corresponding...

Sponsor: First Affiliated Hospital of Zhejiang UniversityEnrolling: 1601 location
RECRUITINGNCT06022913

Behavioural Activation for Bipolar Depression

Bipolar disorder (BD) affects between 1-3% of the world's population. People with BD experience episodes of mania or hypomania and in most cases, they experience periods of...

Sponsor: Reykjavik UniversityEnrolling: 101 location

Frequently Asked Questions

There are currently 12 clinical trials for Bipolar Depression, with 12 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Bipolar Depression, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 2 Phase 3 trials for Bipolar Depression, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.