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Cardiogenic Shock Clinical Trials

22 recruiting trials for Cardiogenic Shock. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
22
Total Trials
22
Recruiting Now
1
Phase 3 Trials
10
Sponsors

Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGEarly Phase 1NCT05700617

Cardiac Power Output in Cardiogenic Shock Patients

The main purpose of this study is to determine whether differences in myocardial reserve predict clinical outcomes for heart failure patients.

Sponsor: University of ChicagoEnrolling: 51 location
RECRUITINGNCT06862700

Effect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock Patients

The goal of this observational study is to learn about the association between vasopressor exposure levels and outcomes in adults with cardiogenic shock receiving VA-ECMO. The...

Sponsor: Xiaotong HouEnrolling: 5341 location
RECRUITINGPhase 2NCT06522594

REMAP ECMO - Beta Receptor Modulation Trial

In this phase 2, single center, randomized clinical pilot trial, investigators will study the effect of a strategy involving a reduction of beta receptor (BR) stimulation (by...

Sponsor: Erasmus Medical CenterEnrolling: 201 location
RECRUITINGNCT05752383

The Clinical and Hemodynamic Course of Cardiogenic Shocks Hospitalized in Critical Care

Cardiogenic shock is a frequent reason for hospitalization in critical care units, with high mortality (50%). Several French registries have been created to improve knowledge of...

Sponsor: Centre Hospitalier Universitaire, AmiensEnrolling: 5001 location
RECRUITINGNCT06644963

IMPELLA, Complications and Tolerance

Myocardial infarction complicated by cardiogenic shock (AMICS) is associated with high morbidity and mortality, and devices like Impella® CP and Impella 5.0-5.5 are often used for...

Sponsor: University Hospital, MontpellierEnrolling: 8001 location
RECRUITINGNCT06645990

Early Left Ventricular unLoading by Impella vs Intra-aortic Balloon Pump

Over the past decade, VA-ECMO has become the main mechanical support for cardiogenic shock (CS) unresponsive to medical therapy. However, recent studies failed to show any...

Sponsor: University Hospital, MontpellierEnrolling: 5001 location
RECRUITINGNCT07266675

Post-Acute Phase of Cardiogenic Shock

Epidemiology studies showed that the burden of cardiogenic shock (CS) persistently high, with increasing annual medical expenses and steady prevalence. In-hospital and one-year...

Sponsor: Mackay Memorial HospitalEnrolling: 3501 location
RECRUITINGNCT05184296

ExtraCorporeal Membrane Oxygenation in the Therapy for REfractory Septic Shock With Cardiac Function Under Estimated

The ECMO-RESCUE study is a prospective, multicenter, non-randomized, cohort study. In this study, we aimed to assessed whether VA-ECMO treatment can improve the 30-day survival...

Sponsor: Second Affiliated Hospital of Guangzhou Medical UniversityEnrolling: 641 location
RECRUITINGNCT06638268

Transcatheter AortiC Valve Implantation in aorTic stenosIs CardiogenIc Shock

The goal of this clinical trial is to learn if acute transcatheter aortic valve implantation (TAVI) is superior to standard treatment (stabilization in an intensive care unit and...

Sponsor: Rigshospitalet, DenmarkEnrolling: 301 location
RECRUITINGNCT07345559

Personalisation of Mean Arterial Pressure in Adult Patients With Cardiogenic Shock

Cardiogenic shock is a life-threatening condition characterized by inadequate cardiac output, leading to organ hypoperfusion and high mortality. Maintaining mean arterial pressure...

Sponsor: CMC Ambroise ParéEnrolling: 40611 locations
RECRUITINGPhase 4NCT05527717

Revascularization Strategy of Multivessel Disease for Patients with Acute Myocardial Infarction Complicated by...

This study is a prospective, open-label, two-arm, randomized multicenter trial to identify whether immediate multi-vessel PCI would be better in clinical outcomes compared with...

Sponsor: Samsung Medical CenterEnrolling: 5601 location
RECRUITINGPhase 3NCT05879276

Effect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization,...

Long term prognosis of cardiogenic shock is related to the resolution of haemodynamic failure, associated visceral failure and the recovery of an adequate myocardial function. In...

Sponsor: Central Hospital, Nancy, FranceEnrolling: 1648 locations
RECRUITINGNCT06162247

Naples Federico II Intensive Cardiac Care Unit Registry (Naples FED2-ICCU Registry)

This protocol proposes to prospectively evaluate current epidemiology, pharmacologic and invasive management and clinical outcomes of patients with acute cardiovascular diseases...

Sponsor: Federico II UniversityEnrolling: 50001 location
RECRUITINGNCT07293923

Magenta Elevate™ Clinical Feasibility Study in Cardiogenic Shock

The Elevate™ CS Clinical Feasibility Study is designed to evaluate the initial safety, effectiveness, and device performance of the Magenta Elevate™ System in patients with...

Sponsor: Magenta Medical Ltd.Enrolling: 105 locations
RECRUITINGNCT06572826

Cardiac Rehabilitation in Patients Acutely Managed for Cardiogenic Shock (ENIGMA)

This is a prospective and retrospective multicentre study conducted under the scientific coordination of the IRCCS Fondazione Don Gnocchi and funded by the Italian Ministry of...

Sponsor: Fondazione Don Carlo Gnocchi OnlusEnrolling: 20001 location
RECRUITINGNCT05146336

CytOSorb TreatMent Of Critically Ill PatientS Registry

Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an...

Sponsor: CytoSorbents, IncEnrolling: 300020 locations
RECRUITINGNCT07515508

Multimodal Phenotyping In Patients Referred With Acute Cardiac faiLurE

The goal of this observational study is to learn whether information collected during routine hospital care, together with blood and urine samples, can help doctors better...

Sponsor: University Heart Center Freiburg - Bad KrozingenEnrolling: 6004 locations
RECRUITINGNCT05298124

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

Mitral regurgitation may be seen in the setting of cardiogenic shock. Transcatheter edge-to-edge repair (TEER) has been shown to improve outcomes in patients with chronic heart...

Sponsor: Ottawa Heart Institute Research CorporationEnrolling: 1444 locations
RECRUITINGNCT05728359

Genomic Determinants of Outcome in Cardiogenic Shock

The aim of this project is to understand the heterogeneity of both the immune consequences and treatment responses in CS. We will explore this heterogeneity through identification...

Sponsor: Barts & The London NHS TrustEnrolling: 3001 location
RECRUITINGNCT05586282

Role of Candidate Proteins in Capillary Leakage During Acute Circulatory Failure

* Testing the association between circulating candidate proteins and the level of vascular leakage for three distinct forms of circulatory failure: cardiogenic shock, septic...

Sponsor: Assistance Publique - Hôpitaux de ParisEnrolling: 3801 location
RECRUITINGNCT06697093

Polish Nationwide Registry of Diagnostics, Treatment and Outcome in Patients With Cardiogenic Shock

The registry objective is to get information on current epidemiology, diagnostics, treatment and outcome in patients with cardiogenic shock in Poland. Obtained information will...

Sponsor: Wroclaw Medical UniversityEnrolling: 5002 locations
RECRUITINGNCT05426083

Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic...

A Clinical Events Committee (CEC) will include Cardiac Surgery Professor and chief of cardiac surgery Rose Kelly MD, Professor of Medicine Ganesh Raveendran MD at the University...

Sponsor: University of MinnesotaEnrolling: 2001 location

Frequently Asked Questions

There are currently 22 clinical trials for Cardiogenic Shock, with 22 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Cardiogenic Shock, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Cardiogenic Shock, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.

For this entity, the underlying data on this page comes from the NIH ClinicalTrials.gov registry. The breakdown above is the federal record; the paragraphs below add the per-entity context that makes the headline numbers usable for a real decision rather than just a data lookup.

Every number on this page links back to the NIH ClinicalTrials.gov registry; the methodology page describes the inputs, refresh cadence, and known limitations of the underlying data product.

Practical use of this page is in combination with the comparison and ranking pages elsewhere on the site, which surface the same data for this entity’s peers within active and historical clinical trials. A single-entity reading without peer context can be misleading when an entity is an outlier on one axis but typical on another.