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Chronic Limb-Threatening Ischemia Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

11 recruiting trials for Chronic Limb-Threatening Ischemia. Eligibility criteria explained in plain English.

TrialFinderData lists 11 Chronic Limb-Threatening Ischemia clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Every phased trial in this set is Phase 2 (1 of the listed studies); the remaining records are observational or have no phase recorded on ClinicalTrials.gov.

Research is led by Acotec Scientific Co., Ltd (1), Cardiovascular and Interventional Radiological Society of Europe (1), R3 Vascular Inc. (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is PCB (device, 1 trial), followed by PTA, Shockwave Medical IVL System.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
11
Total Trials
11
Recruiting Now
0
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT06330493

AcoArt Litos PCB Below-the-knee Global Trial

The objective of this study is to assess whether efficacy of the AcoArt Litos PCB is superior and whether safety of AcoArt Litos PCB is noninferior to the control device (FDA...

Sponsor: Acotec Scientific Co., LtdEnrolling: 28819 locations
RECRUITINGNCT06149650

Chronic Limb-Threatening Ischemia Treated With Intravascular Lithotripsy Observational Study

CALCIO is a multicentre, prospective, observational cohort study that will collect real world data on the use of intravascular Lithotripsy (IVL) with the Shockwave IVL system to...

Sponsor: Cardiovascular and Interventional Radiological Society of EuropeEnrolling: 40020 locations
RECRUITINGNCT06071429

Bioresorbable Sirolimus-Eluting Scaffold Treatment for Below the Knee Disease

The objective of this prospective, single-blinded, randomized controlled trial is to evaluate the safety and efficacy of the MAGNITUDE BRS System for the planned treatment of...

Sponsor: R3 Vascular Inc.Enrolling: 3003 locations
RECRUITINGNCT07330635

Chronic Wounds and Blood Circulation Detection

Lower limb circulatory insufficiency and the associated chronic wounds are common health problems among the elderly. These issues not only affect the individual's mobility and...

Sponsor: National Health Research Institutes, TaiwanEnrolling: 4251 location
RECRUITINGNCT07472049

Symptomatic and Systemic Atherosclerotic Plaque Activity in Patients With Peripheral Arterial Disease Using Novel...

The goal of this observational study is to characterise the relationships between inflammation, microcalcification and thrombus activity in atherosclerotic plaques in peripheral...

Sponsor: University of EdinburghEnrolling: 1001 location
RECRUITINGNCT05313165

PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.

Sponsor: LimFlow, Inc.Enrolling: 10020 locations
RECRUITINGNCT03622359

Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease

The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value of radiotracer-based...

Sponsor: Nationwide Children's HospitalEnrolling: 1921 location
RECRUITINGNCT07068789

Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia

This interventional prospective study aims to assess the effectiveness of single vessel versus multiple vessel infrapopliteal angioplasty in patients with chronic threatening limb...

Sponsor: Sohag UniversityEnrolling: 401 location
RECRUITINGPhase 2NCT07352800

Safety of Antithrombotic Heparin Proteoglycan Mimetic APAC in Peripheral Arterial Occlusive Disease and Chronic...

The goal of this study is to learn if a new medicine (called antiplatelet and anticoagulant \[APAC\]) can help the body to prevent blood clots and whether APAC is safe and well...

Sponsor: Aplagon OyEnrolling: 423 locations
RECRUITINGNCT06879561

Pressure Wire Guidance for Infrapopliteal Artery Interventions

"• A prospective, single-center randomized controlled comparison trial. * A total of 100 patients with symptoms of chronic limb-threatening ischemia (Rutherford category 5)...

Sponsor: Yonsei UniversityEnrolling: 1001 location
RECRUITINGNCT05620095

Durg Coated Balloon Angioplasty in Infrapopliteal Lesions

This study is a multicenter observational study designed to evaluate the the effectiveness and safety of drug-coated balloon (DCB) angioplasty for below the knee arterial lesions...

Sponsor: Liyuan Hospital of Tongji Medical College, Huazhong University of Science and TechnologyEnrolling: 100010 locations

Frequently Asked Questions

There are currently 11 clinical trials for Chronic Limb-Threatening Ischemia, with 11 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Chronic Limb-Threatening Ischemia, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Chronic Limb-Threatening Ischemia, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.