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Chronic Myelomonocytic Leukemia Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

6 recruiting trials for Chronic Myelomonocytic Leukemia. Eligibility criteria explained in plain English.

TrialFinderData lists 6 Chronic Myelomonocytic Leukemia clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 2 is the largest group at 60% (3 studies); the largest phase groups are Phase 2: 3, Phase 1 / Phase 2: 1, Phase 3: 1.

Research is led by Thomas Jefferson University (1), Kirsten Grønbæk (1), University of Birmingham (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Cyclophosphamide (drug, 2 trials), followed by Mycophenolate Mofetil, Placebo.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
6
Total Trials
6
Recruiting Now
1
Phase 3 Trials
6
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 2NCT05031897

Two Step Haplo With Radiation Conditioning

This phase II clinical trial evaluates whether a modified modality of conditioning reduces treatment-related mortality (TRM) in patients who undergo a hematopoietic stem cell...

Sponsor: Thomas Jefferson UniversityEnrolling: 631 location
RECRUITINGPhase 2NCT03999723

Combining Active and Passive DNA Hypomethylation

This is a multicentre, randomized, parallel-group, placebo-controlled, double-blind phase 2 study of the efficacy and safety of oral vitamin C supplement in combination with...

Sponsor: Kirsten GrønbækEnrolling: 19610 locations
RECRUITINGPhase 2NCT04888741

Methods of T Cell Depletion Trial (MoTD)

A multi-centre phase II trial of GvHD prophylaxis following unrelated donor stem cell transplantation comparing Thymoglobulin vs. Calcineurin inhibitor or Sirolimus-based...

Sponsor: University of BirminghamEnrolling: 40017 locations
RECRUITINGPhase 1 / Phase 2NCT06159491

Pacritinib in CMML

This is a phase 1/2 trial of pacritinib in combination with azacitidine in patients with Chronic Myelomonocytic Leukemia (CMML). Patients will be newly diagnosed or previously...

Sponsor: Douglas TremblayEnrolling: 261 location
RECRUITINGPhase 3NCT06647862

IMM01+Azacitidine VS Placebo +Azacitidine in Patients With Newly Diagnosed Chronic Myelomonocytic Leukemia (CMML1-2)

This study is a randomized, controlled, double-blind, multicenter, phase Ⅲ clinical study to evaluate the efficacy of IMM01(timdarpacept) in combination with azacitidine versus...

Sponsor: ImmuneOnco Biopharmaceuticals (Shanghai) Inc.Enrolling: 17020 locations
RECRUITINGNCT06111612

Intensive Conditioning withTHI/Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary Involvement

This study is a multicenter, single-arm, prospective phase II clinical trial that evaluates the efficacy and safety of an intensive conditioning regimen with thiotepa combined...

Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineEnrolling: 501 location

Frequently Asked Questions

There are currently 6 clinical trials for Chronic Myelomonocytic Leukemia, with 6 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Chronic Myelomonocytic Leukemia, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Chronic Myelomonocytic Leukemia, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.