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Duchenne Muscular Dystrophy (dmd) Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

19 recruiting trials for Duchenne Muscular Dystrophy (dmd). Eligibility criteria explained in plain English.

TrialFinderData lists 19 Duchenne Muscular Dystrophy (dmd) clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Early Phase 1 is the largest group at 50% (3 studies); the largest phase groups are Early Phase 1: 3, Phase 1 / Phase 2: 2, Phase 3: 1.

Research is led by Entrada Therapeutics, Inc. (2), Shanghai Jiao Tong University School of Medicine (2), Aristotle University Of Thessaloniki (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Monitoring of NIV at home (diagnostic_test, 1 trial), followed by Observational Assessment, MAIJU.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
19
Total Trials
19
Recruiting Now
1
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT07515235

DMD Gene Variants and Cardiac Dysfunction in Young Males With Dystrophinopathies

The goal of this observational study is to investigate whether the type, location, and extent of pathogenic variants in the DMD gene are associated with cardiac dysfunction in...

Sponsor: Aristotle University Of ThessalonikiEnrolling: 651 location
RECRUITINGNCT06925269

DMD Voice: Qualitative Interviews With Patients and Caregivers

The purpose of this study is to understand DMD functional losses or abilities and their association with independence and quality of life from the perspective of individuals with...

Sponsor: Red Nucleus Enterprise Solutions, LLCEnrolling: 681 location
RECRUITINGNCT06773988

Follow-up of NIV At Home in Patients with Duchenne Muscular Dystrophy

The aim of this study is to verify whether full video home polysomnography (sleep study) with nocturnal transcutaneous CO2 monitoring is feasible in the follow-up of non-invasive...

Sponsor: Universitaire Ziekenhuizen KU LeuvenEnrolling: 171 location
RECRUITINGNCT06755138

Research on the Relationship Between Scoliosis, Pain, Quality of Life, and Trunk Muscle Compensation Patterns Among...

* Objective: The objective of this observational study is to evaluate and quantify trunk muscle compensatory movement patterns in patients with Duchenne Muscular Dystrophy (DMD)...

Sponsor: Seoul National University HospitalEnrolling: 301 location
RECRUITINGNCT07286565

Active NBS Study: Decentralised Monitoring Motor Development in Children With Duchenne Muscular Dystrophy or Spinal...

The Active NBS Liege study is a monocentric, academic, fully remote, observational study designed to validate digital measures of motor development in children with spinal...

Sponsor: Centre Hospitalier Universitaire de LiegeEnrolling: 1001 location
RECRUITINGNCT07332013

Urinary Titin Biomarker in DMD

A universal challenge in clinical investigation of novel therapeutics is the need for quantitative, objective biomarkers that directly address the mechanisms of disease and...

Sponsor: Children's Hospital of PhiladelphiaEnrolling: 501 location
RECRUITINGNCT07609394

Duchenne Electronic Health Record Study

This study aims to collect retrospective and prospective, long-term data of patients with dystrophinopathy (including Duchenne, Becker, and female carriers) through electronic...

Sponsor: The Duchenne RegistryEnrolling: 250010 locations
RECRUITINGPhase 1 / Phase 2NCT07037862

A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping to Evaluate the Safety and...

This is a study of the investigational medicine ENTR-601-44 in participants who have Duchenne muscular dystrophy (DMD), a rare genetic condition. The researchers want to: Test...

Sponsor: Entrada Therapeutics, Inc.Enrolling: 2414 locations
RECRUITINGPhase 3NCT07608432

Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered Intravenously Every 4 Weeks in...

The purpose of the study is to assess the efficacy, safety, and tolerability of zeleciment rostudirsen (DYNE-251) administered intravenously (IV) every 4 weeks to ambulatory...

Sponsor: Dyne TherapeuticsEnrolling: 901 location
RECRUITINGEarly Phase 1NCT06641895

Evaluation of the Safety and Efficacy of BBM-D101 to Treat Patients with Duchenne Muscular Dystrophy

The purpose of the study is to assess the safety, tolerability, and efficacy of BBM-D101 to treat patients with Duchenne Muscular Dystrophy.

Sponsor: Shanghai Jiao Tong University School of MedicineEnrolling: 61 location
RECRUITINGNCT07467187

Invasive Home Ventilation in Denmark

The aim of this study is to describe national trends over the past 10 years in patients receiving invasive home mechanical ventilation (HMV) in Denmark. This includes indications...

Sponsor: Rigshospitalet, DenmarkEnrolling: 4501 location
RECRUITINGNCT07039799

The Effect of Virtual Reality Applications on Upper Extremity Functions in Patients With Duchenne Muscular Dystrophy

This study aims to evaluate the effects of fully immersive virtual reality (VR) applications on upper extremity (UE) functions in individuals diagnosed with Duchenne Muscular...

Sponsor: Istanbul UniversityEnrolling: 361 location
RECRUITINGEarly Phase 1NCT07188012

Safety and Dystrophin Expression of SPOT-03 in Duchenne Muscular Dystrophy (DMD) Patients

The primary objective of this study is to evaluate the safety and tolerability of SPOT-03 administered by intravenous (IV) infusion to DMD patients. In addition, this study will...

Sponsor: Shanghai Siponuoyin Biotechnology Co LtdEnrolling: 91 location
RECRUITINGNCT07423026

A Remote Study Using Technology to Assess Outcomes in DMD

Every year, 100 boys are born in the UK with a rare muscle disease called Duchenne muscular dystrophy. These boys cannot make an important muscle protein called dystrophin. They...

Sponsor: University of OxfordEnrolling: 601 location
RECRUITINGNCT07129954

Fear of Falling in Muscular Dystrophy

Primary objectives WP1: Evaluate the prevalence of FOF in the study population and how this varies over time. Evaluate whether there are relationships between the variables...

Sponsor: Universita di VeronaEnrolling: 1001 location
RECRUITINGNCT06839469

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

The purpose of this research is (1) to identify disease specific walking-related digital biomarkers of disease severity, and (2) monitor longitudinal changes in natural...

Sponsor: Columbia UniversityEnrolling: 1063 locations
RECRUITINGNCT07092540

The Baby Duchenne Study: Characterizing Developmental and Clinical Outcomes in the First Three Years in Children With...

The aim of the BABY DUCHENNE study is to evaluate the natural history and characterize the early clinical outcomes in very young children (0-3 years) with Duchenne muscular...

Sponsor: University of RochesterEnrolling: 1051 location
RECRUITINGEarly Phase 1NCT06900049

Evaluation of the Safety, Tolerability, and Efficacy of LE051 in Patients With Duchenne Muscular Dystrophy

The purpose of this study is to evaluate the safety, tolerability, and efficacy of LE051 intravenous therapy in DMD patients treated with exon 51 skipping therapy.

Sponsor: Shanghai Jiao Tong University School of MedicineEnrolling: 121 location
RECRUITINGPhase 1 / Phase 2NCT07038824

A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping to Evaluate the Safety and...

This is a study of the investigational medicine ENTR-601-45 in participants who have Duchenne muscular dystrophy (DMD), a rare genetic condition. The researchers want to: Test how...

Sponsor: Entrada Therapeutics, Inc.Enrolling: 2415 locations

Frequently Asked Questions

There are currently 19 clinical trials for Duchenne Muscular Dystrophy (dmd), with 19 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Duchenne Muscular Dystrophy (dmd), review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Duchenne Muscular Dystrophy (dmd), representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.