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TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Generalized Myasthenia Gravis (gMG) Clinical Trials

6 recruiting trials for Generalized Myasthenia Gravis (gMG). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
6
Total Trials
6
Recruiting Now
1
Phase 3 Trials
5
Sponsors

Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT07294170

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in...

ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work for people with myasthenia gravis. The goal is to find the best...

Sponsor: argenxEnrolling: 705 locations
RECRUITINGEarly Phase 1NCT07058298

GC012F Injection in the Treatment of Refractory Generalized Myasthenia Gravis(24103)

This is a single-arm, open-label and early exploratory clinical study, with the purpose to study the safety, tolerability and initial clinical efficacy of GC012F Injection in the...

Sponsor: Daishi TianEnrolling: 61 location
RECRUITINGNCT06312644

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

The primary objective of this study is to describe the frequency and characteristics of pregnancy outcomes and maternal complications among participants exposed to Ultomiris and...

Sponsor: Alexion Pharmaceuticals, Inc.Enrolling: 758 locations
RECRUITINGNCT07247279

Epidemiological Study of Treatment Approaches in AChR-Antibody Positive Generalized Myasthenia Gravis in Russia

This is a multicenter, non-interventional, retrospective-prospective, single-arm observational study designed to describe real-world treatment approaches and clinical outcomes...

Sponsor: AstraZenecaEnrolling: 4503 locations
RECRUITINGPhase 3NCT07215949

Zilucoplan for Severe gMG Exacerbations

This is an open-label, multicenter, interventional phase 3b study in participants with AChR+ gMG and severe exacerbation that require hospitalization. Patients will receive...

Sponsor: Miriam FreimerEnrolling: 151 location
RECRUITINGPhase 2NCT07284420

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With...

This study is part of the ADAPT Forward platform study (NCT07294170). ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work...

Sponsor: argenxEnrolling: 705 locations

Frequently Asked Questions

There are currently 6 clinical trials for Generalized Myasthenia Gravis (gMG), with 6 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Generalized Myasthenia Gravis (gMG), review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Generalized Myasthenia Gravis (gMG), representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice — always talk to your doctor about clinical trial participation.