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Heart Failure With Preserved Ejection Fraction Clinical Trials

10 recruiting trials for Heart Failure With Preserved Ejection Fraction. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
10
Total Trials
10
Recruiting Now
2
Phase 3 Trials
10
Sponsors

Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT04587648

Cardiac Amyloidosis in HFpEF

Heart failure with preserved ejection fraction (HFpEF) accounts for half of heart failure cases with heterogenous cause and variable presentations. The diagnosis of HFpEF required...

Sponsor: National Taiwan University HospitalEnrolling: 2501 location
RECRUITINGPhase 1NCT06061549

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction

The goal of this clinical trial is to test an experimental gene therapy in participants with heart failure with preserved ejection fraction, also known as diastolic heart failure....

Sponsor: Sardocor Corp.Enrolling: 102 locations
RECRUITINGNCT04237701

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System

The Yale HF Registry is a live EHR based registry that allows for retrospective and real-time monitoring of Heart Failure case across the Yale New Haven Health System.

Sponsor: Yale UniversityEnrolling: 400001 location
RECRUITINGPhase 3NCT07037459

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

This trial will examine if maridebart cafraglutide as an adjunct to standard of care will lead to a reduction in heart failure (HF) events such as HF hospitalizations and urgent...

Sponsor: AmgenEnrolling: 505620 locations
RECRUITINGNCT06337812

Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)

The study team is studying how increasing dietary fiber, specifically through adding potato starch to participant's diet, may impact the species of bacteria in participant's gut...

Sponsor: University of MichiganEnrolling: 301 location
RECRUITINGNCT05878912

The Effect of Obesity and Weight Loss in Heart Failure With Preserved Ejection Fraction

This study looks at the effects of weight loss in people who have heart failure with preserved ejection fraction (HFpEF) and are overweight or obese. The main questions it aims...

Sponsor: University of OxfordEnrolling: 1201 location
RECRUITINGNCT06479876

Home-Based Cardiac Rehabilitation for Patients With Heart Failure

The vast majority of individuals with heart failure do not participate in center based cardiac rehabilitation (CBCR). While steps to increase utilization of CBCR are important,...

Sponsor: Vanderbilt University Medical CenterEnrolling: 1001 location
RECRUITINGPhase 3NCT02901184

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart...

Sponsor: Uppsala UniversityEnrolling: 200020 locations
RECRUITINGPhase 2NCT06369298

Study of JK07 in Patients With Chronic Heart Failure

This is a Phase 2, randomized, double-blind, placebo-controlled, multiple dose study to assess the safety, tolerability, and efficacy of JK07 in participants aged 18-85 with heart...

Sponsor: Salubris Biotherapeutics IncEnrolling: 28220 locations
RECRUITINGNCT06409585

Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition

Heart scarring, also known as fibrosis, plays a major role in a lot of heart muscle abnormalities. These abnormalities of the heart muscle can lead to major issues such as...

Sponsor: University of EdinburghEnrolling: 2901 location

Frequently Asked Questions

There are currently 10 clinical trials for Heart Failure With Preserved Ejection Fraction, with 10 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Heart Failure With Preserved Ejection Fraction, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 2 Phase 3 trials for Heart Failure With Preserved Ejection Fraction, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice — always talk to your doctor about clinical trial participation.