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Heart Failure With Reduced Ejection Fraction Clinical Trials

12 recruiting trials for Heart Failure With Reduced Ejection Fraction. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
12
Total Trials
12
Recruiting Now
1
Phase 3 Trials
10
Sponsors

Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT04237701

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System

The Yale HF Registry is a live EHR based registry that allows for retrospective and real-time monitoring of Heart Failure case across the Yale New Haven Health System.

Sponsor: Yale UniversityEnrolling: 400001 location
RECRUITINGNCT06344910

PRagmatic Study Of Messaging to Providers of Patients With Heart Failure in Amsterdam UMC

This is a prospective cohort study, where the investigators aim to investigate the effect of implementation of an electronic nudge alerting clinicians to the prescription of the 4...

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Enrolling: 9002 locations
RECRUITINGNCT06552637

Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure

RECOVER HF is a clinical study designed to evaluate the safety and efficacy of Synchronized Diaphragmatic Stimulation delivered using the VisONE System in the treatment of...

Sponsor: VisCardia Inc.Enrolling: 2701 location
RECRUITINGNCT06384963

Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF

The goal of this clinical trial is to test a new type of pacemaker in heart failure patients following a heart bypass operation. The new pacemaker restores respiratory sinus...

Sponsor: Ceryx Medical AustraliaEnrolling: 543 locations
RECRUITINGPhase 3NCT06736574

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

The purpose of this study is to find out if the investigational drug called omecamtiv mecarbil can reduce the risk of the effects of heart failure, like hospitalization,...

Sponsor: CytokineticsEnrolling: 180020 locations
RECRUITINGNCT07275931

Digital Support Program for Patients With Heart Failure - a Cluster-Randomized Hybrid Type 2 Study

The overall aim of this project is to evaluate the effects of a digital support program for patients with heart failure through a cluster-randomized controlled trial, and to...

Sponsor: Linkoeping UniversityEnrolling: 2401 location
RECRUITINGNCT06479876

Home-Based Cardiac Rehabilitation for Patients With Heart Failure

The vast majority of individuals with heart failure do not participate in center based cardiac rehabilitation (CBCR). While steps to increase utilization of CBCR are important,...

Sponsor: Vanderbilt University Medical CenterEnrolling: 1001 location
RECRUITINGNCT05609097

PRIME HFrEF: Novel Exercise for Older Patients With Heart Failure With Reduced Ejection Fraction

This study is trying to find out whether performing a hybrid aerobic-resistance exercise training program (titled PRIME: Peripheral Remodeling via Intermittent Muscular Exercise)...

Sponsor: University of VirginiaEnrolling: 921 location
RECRUITINGPhase 2NCT06369298

Study of JK07 in Patients With Chronic Heart Failure

This is a Phase 2, randomized, double-blind, placebo-controlled, multiple dose study to assess the safety, tolerability, and efficacy of JK07 in participants aged 18-85 with heart...

Sponsor: Salubris Biotherapeutics IncEnrolling: 28220 locations
RECRUITINGNCT06299436

Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure

Right ventricular (RV) failure is recognized to worsen patient outcomes in the setting of heart failure with reduced ejection fraction (HFrEF)-related pulmonary hypertension (PH),...

Sponsor: Johns Hopkins UniversityEnrolling: 501 location
RECRUITINGNCT05828719

Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction

Randomized trial to compare clinical outcomes between revascularization versus medical treatment alone in patients with ischemic cardiomyopathy and left ventricular dysfunction.

Sponsor: Samsung Medical CenterEnrolling: 9001 location
RECRUITINGNCT06078436

Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEF

This study aims to compare the impact of hemodynamic monitoring using pulmonary artery catheter (PAC) on survival and inotropic agent reduction in patients with cardiogenic shock...

Sponsor: Min-Seok KimEnrolling: 1601 location

Frequently Asked Questions

There are currently 12 clinical trials for Heart Failure With Reduced Ejection Fraction, with 12 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Heart Failure With Reduced Ejection Fraction, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Heart Failure With Reduced Ejection Fraction, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice — always talk to your doctor about clinical trial participation.