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Malaria Falciparum Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

8 recruiting trials for Malaria Falciparum. Eligibility criteria explained in plain English.

TrialFinderData lists 8 Malaria Falciparum clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 is the largest group at 67% (4 studies); the largest phase groups are Phase 1: 4, Phase 3: 1, Phase 1 / Phase 2: 1.

Research is led by University of Oxford (2), Medicines for Malaria Venture (1), London School of Hygiene and Tropical Medicine (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is MMV055 Dose 1 (drug, 1 trial), followed by MMV055 Dose 2, MMV055 Dose 3.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
8
Total Trials
8
Recruiting Now
1
Phase 3 Trials
7
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 1NCT07011511

Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of LAI MMV055 Alone and in...

This is a single-centre, participant- and investigator-blind, randomised, placebo controlled, single ascending dose study to assess the safety, tolerability and PK of a single...

Sponsor: Medicines for Malaria VentureEnrolling: 721 location
RECRUITINGPhase 3NCT06923592

Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar

The resilience of P. vivax to malaria elimination efforts is due to its ability to form dormant liver stages (hypnozoites) that reactivate weeks to months after the initial...

Sponsor: London School of Hygiene and Tropical MedicineEnrolling: 192002 locations
RECRUITINGPhase 1NCT06958198

A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria...

This is a Phase Ib age de-escalation, dose escalation, open-label study to assess the safety and immunogenicity of the multi-stage malaria vaccine candidate R21 plus RH5.1 and/or...

Sponsor: University of OxfordEnrolling: 561 location
RECRUITINGPhase 1NCT06862453

Safety, Tolerability and Efficacy of PfSPZ-LARC2 Vaccine Against CHMI in Malaria-Naïve Adults

This is a randomized, double-blind, placebo-controlled Phase 1 trial of Plasmodium falciparum (Pf) sporozoite (SPZ) late-arresting replication-competent (LARC) malaria vaccine...

Sponsor: Sanaria Inc.Enrolling: 581 location
RECRUITINGPhase 1NCT06171113

A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants

The primary purpose of the study is to characterise the safety of GSK4024484 in healthy participants within a controlled pharmacokinetic (PK) range, and the effect of food on the...

Sponsor: GlaxoSmithKlineEnrolling: 1561 location
RECRUITINGPhase 1 / Phase 2NCT05790889

A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso.

This is a Phase IIb randomised controlled trial of the safety, immunogenicity and efficacy of the blood-stage malaria vaccine candidates RH5.1 in Matrix-MTM and RH5.2-VLP in...

Sponsor: University of OxfordEnrolling: 4801 location
RECRUITINGNCT07389057

Assessing the Feasibility of Combining Dihydroartemisinin Piperaquine and Primaquine for Malaria Mass Drug...

Previous malaria control studies in Ghana have shown that community-wide approaches can substantially reduce malaria infections. In a mass testing, treatment and tracking (MTTT)...

Sponsor: Noguchi Memorial Institute for Medical ResearchEnrolling: 90001 location
RECRUITINGNCT07009847

An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine

This is an observational case-control study to assess the effectiveness of the R21/Matrix-M vaccine against severe malaria, clinical malaria (in high transmission perennial...

Sponsor: Serum Institute of India Pvt. Ltd.Enrolling: 23085 locations

Frequently Asked Questions

There are currently 8 clinical trials for Malaria Falciparum, with 8 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Malaria Falciparum, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Malaria Falciparum, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.