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Neovascular Age-related Macular Degeneration Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

9 recruiting trials for Neovascular Age-related Macular Degeneration. Eligibility criteria explained in plain English.

TrialFinderData lists 9 Neovascular Age-related Macular Degeneration clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 / Phase 2 is the largest group at 43% (3 studies); the largest phase groups are Phase 1 / Phase 2: 3, Phase 3: 3, Phase 2: 1.

Research is led by Hoffmann-La Roche (2), Sanofi (1), Jaeb Center for Health Research (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is SAR402663 (biological, 1 trial), followed by Diluent, Faricimab.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
9
Total Trials
9
Recruiting Now
3
Phase 3 Trials
8
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 1 / Phase 2NCT06660667

A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration

This is a Phase 1/Phase 2 multicenter study to evaluate the safety and efficacy of a one-time single-eye intravitreal dose of SAR402663 in participants with neovascular...

Sponsor: SanofiEnrolling: 6618 locations
RECRUITINGNCT06680817

A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)

The FaReal study aims to evaluate the effectiveness, safety, clinical insights and treatment patterns in patients treated with faricimab, in neovascular age-related macular...

Sponsor: Hoffmann-La RocheEnrolling: 85020 locations
RECRUITINGPhase 3NCT05904028

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

Home optical coherence tomography- guided treatment versus treat and extend for the management of neovascular age-related macular degeneration.

Sponsor: Jaeb Center for Health ResearchEnrolling: 60020 locations
RECRUITINGPhase 1 / Phase 2NCT06492863

Gene Therapy(FT-003) for Wet AMD

The goal of this clinical trial is to evaluate the safety, tolerability and efficacy of disposable vitreous injection of FT-003 in subjects with neovascular age-related Macular...

Sponsor: Frontera TherapeuticsEnrolling: 781 location
RECRUITINGPhase 2NCT07275840

A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD

This study is designed for Open-label, multi-center, single-arm Phase II trail to evaluate the efficacy and safety of intravitreal injection of IBI302 in nAMD patients.

Sponsor: Innovent Biologics Technology Limited (Shanghai R&D Center)Enrolling: 8001 location
RECRUITINGPhase 3NCT03683251

Extension Study for the Port Delivery System With Ranibizumab (Portal)

This study will evaluate the long-term safety and tolerability of the Port Delivery System with ranibizumab (PDS) (100 mg/mL) in participants with neovascular age-related macular...

Sponsor: Hoffmann-La RocheEnrolling: 100020 locations
RECRUITINGPhase 3NCT07614776

A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in...

The aim of this trial is to demonstrate similarity in efficacy between ABP 938 8 mg and aflibercept (US) 8 mg by evaluating the change in best corrected visual acuity (BCVA) in...

Sponsor: AmgenEnrolling: 30420 locations
RECRUITINGPhase 1 / Phase 2NCT07547228

A Study of PRL3-zumab in Neovascular Age-related Macular Degeneration (nAMD)

Study Design This is a Single-center, Phase I/II placebo-controlled study to assess the safety and efficacy of PRL3-zumab in patients with Neovascular Age-related Macular...

Sponsor: Intra-IMMUSG Pte LtdEnrolling: 151 location
RECRUITINGNCT06929507

Impact of Intravitreal Faricimab on Renal Function in Diabetic Patients

This study aims to investigate the impact of intravitreal injection of anti-vascular endothelial growth factor (anti VEGF) Faricimab on renal function of diabetic patients....

Sponsor: University Hospital, AlexandroupolisEnrolling: 602 locations

Frequently Asked Questions

There are currently 9 clinical trials for Neovascular Age-related Macular Degeneration, with 9 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Neovascular Age-related Macular Degeneration, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 3 Phase 3 trials for Neovascular Age-related Macular Degeneration, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.