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Non-Proliferative Diabetic Retinopathy Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

4 recruiting trials for Non-Proliferative Diabetic Retinopathy. Eligibility criteria explained in plain English.

TrialFinderData lists 4 Non-Proliferative Diabetic Retinopathy clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 3 is the largest group at 67% (2 studies); the largest phase groups are Phase 3: 2, Phase 2: 1.

Research is led by Ocular Therapeutix, Inc. (1), Annexin Pharmaceuticals AB (1), Beletalent (Zhuhai) Pharmaceutical Co., Ltd (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Single intravitreal injection of axitinib hydrogel implant followed by a mock (sham) injection procedure at Week 24 (drug, 1 trial), followed by Intravitreal injection of axitinib hydrogel implant followed by a second intravitreal injection of the axitinib implant at Week 24, Sham/mock procedure of intravitreal injection followed by a second sham/mock procedure at Week 24.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
4
Total Trials
4
Recruiting Now
2
Phase 3 Trials
4
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 3NCT07235085

A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Participants With Non-Proliferative...

The purpose of this trial is to study the safety and effectiveness of OTX-TKI (axitinib intravitreal hydrogel) for the treatment of Non-Proliferative Diabetic Retinopathy....

Sponsor: Ocular Therapeutix, Inc.Enrolling: 9301 location
RECRUITINGPhase 2NCT07259928

Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Diabetic Retinopathy or Retinal Vein Occlusion

The goal of this clinical trial is to learn about the safety of the investigational medicinal product ANXV. It will also learn about how ANXV works to treat non-proliferative...

Sponsor: Annexin Pharmaceuticals ABEnrolling: 121 location
RECRUITINGPhase 3NCT06817265

Clinical Study on the Efficacy and Safety of TNTL in the Treatment of Non-proliferative Diabetic Retinopathy

The goal of this clinical trial is to learn if drug TNTL works to treat non-proliferative diabetic retinopathy in adults. It will also learn about the safety of drug TNTL. The...

Sponsor: Beletalent (Zhuhai) Pharmaceutical Co., LtdEnrolling: 36020 locations
RECRUITINGNCT06713720

Remote Ischemic Conditioning for Non-Proliferative Diabetic Retinopathy

The goal of this clinical trial is to evaluate whether remote ischemic conditioning (RIC) is a safe and effective treatment for non-proliferative diabetic retinopathy (NPDR) in...

Sponsor: Xuxiang Zhang, MDEnrolling: 682 locations

Frequently Asked Questions

There are currently 4 clinical trials for Non-Proliferative Diabetic Retinopathy, with 4 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Non-Proliferative Diabetic Retinopathy, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 2 Phase 3 trials for Non-Proliferative Diabetic Retinopathy, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.