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Peripheral Arterial Disease Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

31 recruiting trials for Peripheral Arterial Disease. Eligibility criteria explained in plain English.

TrialFinderData lists 31 Peripheral Arterial Disease clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 4 is the largest group at 33% (2 studies); the largest phase groups are Phase 4: 2, Phase 1 / Phase 2: 2, Phase 3: 1, Phase 2: 1.

Research is led by University of Nebraska (3), Shahid Baba (2), Mersin Medicalpark Hastanesi (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Carnosine (drug, 2 trials), followed by Radial and Ulnar Artery Access, iABC platform use.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
31
Total Trials
31
Recruiting Now
1
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT07614386

Radial Access Data in Vascular Interventions Registry

The RADIUS study is a prospective observational registry designed to collect real-world data regarding radial and ulnar artery access in percutaneous vascular interventions. The...

Sponsor: Mersin Medicalpark HastanesiEnrolling: 200001 location
RECRUITINGNCT06775028

Integrated Approach in Frail Older People with Atrial Fibrillation

The study will verify if a structured multidisciplinary approach (called iABC), aimed to improve the appropriate management of elderly AF patients with multimorbidity (the i-ABC...

Sponsor: Heart Care FoundationEnrolling: 125020 locations
RECRUITINGNCT07144150

EVERO Drug-coated Balloon (DCB) Randomized Trial

The primary objective of the study is to evaluate the long-term safety and effectiveness of the Advance Evero™ 18 Everolimus-coated Percutaneous Transluminal Angioplasty Balloon...

Sponsor: Cook Research IncorporatedEnrolling: 4104 locations
RECRUITINGNCT06952543

Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

The purpose of this study is to develop a new noninvasive tool for early diagnosis of Peripheral Arterial Disease (PAD) and use the proposed method for monitoring the disease...

Sponsor: Mayo ClinicEnrolling: 4001 location
RECRUITINGPhase 4NCT02842424

Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis

Peripheral artery disease (PAD) is a manifestation of atherosclerosis that produces progressive narrowing and occlusion of the arteries supplying the lower extremities. The most...

Sponsor: University of NebraskaEnrolling: 701 location
RECRUITINGNCT07122167

Post-market Registry Study on the Safety and Efficacy of ZENFLEX Pro™ Peripheral Drug-eluting Stent System for...

This is a prospective, multi-center, single-arm post-market study evaluating the safety and effectiveness of the ZENFLEX Pro™ Drug-eluting Stent in treating femoropopliteal artery...

Sponsor: MDCECRO LLCEnrolling: 1531 location
RECRUITINGPhase 3NCT04774159

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

The Low dose ColchicinE in pAtients with peripheral Artery DiseasE to address residual vascular Risk (LEADER-PAD) trial will evaluate if anti-inflammatory therapy with colchicine...

Sponsor: Population Health Research InstituteEnrolling: 615020 locations
RECRUITINGNCT06409949

MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology

In our research, we are delving into whether taking MitoQ for six months can improve the symptoms and function of people diagnosed with peripheral artery disease, especially those...

Sponsor: University of NebraskaEnrolling: 601 location
RECRUITINGNCT04793581

Assessment of the Utility of the Pantheris Small Vessel (SV) System

A single-arm study to assess the utility of the Pantheris SV catheter in addressing peripheral artery disease in arteries located below the knee. Data will be collected on the...

Sponsor: Avinger, Inc.Enrolling: 602 locations
RECRUITINGNCT07497360

Tele-assessment and Face-to-face Assessment of the 30-second Sit-stand Test in Peripheral Artery Disease

Peripheral artery disease (PAD) is a chronic and progressive condition caused by narrowing or blockage of arteries in the lower limbs due to atherosclerosis. It primarily affects...

Sponsor: Izmir Democracy UniversityEnrolling: 451 location
RECRUITINGNCT06573437

Clinical Performance of the VESTO® Vascular Stent for Treatment of Iliac Peripheral Obstructive Arterial Disease

This study will validate the efficacy and safety of the VESTO® Vascular Stent for treating patients with iliac peripheral arterial obstructive disease in a post-market clinical...

Sponsor: Braile Biomedica Ind. Com. e Repr. Ltda.Enrolling: 1006 locations
RECRUITINGNCT07472049

Symptomatic and Systemic Atherosclerotic Plaque Activity in Patients With Peripheral Arterial Disease Using Novel...

The goal of this observational study is to characterise the relationships between inflammation, microcalcification and thrombus activity in atherosclerotic plaques in peripheral...

Sponsor: University of EdinburghEnrolling: 1001 location
RECRUITINGNCT05313165

PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.

Sponsor: LimFlow, Inc.Enrolling: 10020 locations
RECRUITINGNCT06009276

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

The purpose of the study is to determine associations between fitness status, bacteria in the mouth, and the blood flow to muscle. This study is trying to find out if fitness...

Sponsor: University of VirginiaEnrolling: 701 location
RECRUITINGPhase 1 / Phase 2NCT06480760

Effects of Carnosine In Patients With Peripheral Arterial Disease Patients

The purpose of this study is to determine whether carnosine (a food ingredient found in chicken and red meat) supplementation (2 g) for 6 months in participants with...

Sponsor: Shahid BabaEnrolling: 1443 locations
RECRUITINGNCT05391815

This Study is a Prospective, Multi-center, Real World, Observational Study, Which Aims at Evaluating Intermediate and...

This study is a prospective, multi-center, real world, observational study, which aims at evaluating the intermediate and long-term efficacy of endovascular treatment for TASC...

Sponsor: Shanghai Zhongshan HospitalEnrolling: 8001 location
RECRUITINGNCT07161583

Advanta VXT and Flixene PMCF Registry

The purpose of the registry is to evaluate the long-term safety and performance of Advanta VXT and Flixene vascular grafts for repair or replacement of peripheral arteries. This...

Sponsor: Atrium Medical CorporationEnrolling: 10002 locations
RECRUITINGNCT05437562

Randomized Clinical Trial for Ewing Amputation in the VA

This study follows the Pilot Investigation of Ewing Amputation for Veterans with PAD Undergoing a Below Knee Amputation. The 2 year pilot feasibility phase has concluded...

Sponsor: VA Office of Research and DevelopmentEnrolling: 1203 locations
RECRUITINGNCT07335341

Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System

The purpose of Case-Specific Health Care Professional (HCP) Clinical Survey of Liberant™ Thrombectomy System, also known as the Liberant Clinical Assessment, is to collect...

Sponsor: Medtronic EndovascularEnrolling: 502 locations
RECRUITINGNCT05612945

High-intensity Intervals Versus Low-to-moderate-intensity Exercise Training in Patients With PAD

Supervised exercise training (SET) is considered among first-line therapies for patients with symptomatic lower extremity peripheral artery disease (PAD), combined with general...

Sponsor: Centre Hospitalier Universitaire VaudoisEnrolling: 601 location
RECRUITINGPhase 1 / Phase 2NCT05371145

Carnosine for Peripheral Arterial Disease Patients

Oral supplementation of L-carnosine will increase muscle carnosine, stabilize HIF1-alpha promote angiogenesis, and thus improve the functioning of lower extremities in PAD...

Sponsor: Shahid BabaEnrolling: 201 location
RECRUITINGNCT05811364

The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare...

The objective of this prospective, multicenter, randomized, controlled clinical trial is to demonstrate the superiority of the VBX Device for primary patency when compared to bare...

Sponsor: W.L.Gore & AssociatesEnrolling: 24420 locations
RECRUITINGPhase 2NCT07318155

A Study of SRSD107 in Participants With Chronic Coronary and/or Peripheral Arterial Disease

The study is a Phase 2a, randomized, double-blind, placebo-controlled, sequential cohort study to evaluate the pharmacodynamics (PD), safety and pharmacokinetics (PK) of multiple...

Sponsor: Sirius Therapeutics Co., Ltd.Enrolling: 1041 location
RECRUITINGNCT06410521

Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease

Peripheral arterial disease (PAD) is characterised as an atherosclerotic disease, most common in the lower limbs (aortoiliac, femoropopliteal, and infrapopliteal arterial...

Sponsor: University of Trás-os-Montes and Alto DouroEnrolling: 403 locations
RECRUITINGNCT06806540

The Frequency of Peripheral Arterial Disease in Patients with Deep Vein Thrombosis of the Lower Limbs

The aim of the study is to assess the frequency of Peripheral Arterial Disease (PAD) and cardiovascular risk factors in patients with unprovoked Deep Vein Thrombosis (DVT) of the...

Sponsor: IRCCS Azienda Ospedaliero-Universitaria di BolognaEnrolling: 4401 location
RECRUITINGNCT07427108

Road Mapping Guided Puncture Versus Ultrasound Guided Puncture During Retrograde Angioplasty Feasibility and Safety

The study aims to compare the technical feasibility and safety of road mapping-guided versus ultrasound-guided retrograde arterial puncture in patients with (CLTI) as measured by:...

Sponsor: Sohag UniversityEnrolling: 321 location
RECRUITINGNCT06566976

Prehabilitation and Rehabilitation in PAD

To determine the effectiveness of pre and post-operative exercise therapy in patients undergoing peripheral artery stenting for peripheral arterial disease.

Sponsor: Palo Alto Veterans Institute for ResearchEnrolling: 3001 location
RECRUITINGNCT05868161

Pounce™ Thrombectomy System Retrospective Registry

The PROWL registry is an open-label retrospective, multi-center, US study of the Surmodics™ Pounce™ Thrombectomy System for the non-surgical removal of emboli and thrombi in the...

Sponsor: SurModics, Inc.Enrolling: 5009 locations
RECRUITINGNCT06480786

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

Peripheral arterial disease (PAD) affects over 230 million adults worldwide and is a highly morbid, costly, and disabling condition. Ischemic leg pain drives disability in PAD...

Sponsor: University of NebraskaEnrolling: 151 location
RECRUITINGPhase 4NCT06873321

VTE Incidence After Rivaroxaban + Aspirin or SAPT After Lower-limb Revascularization

Venous thromboembolism (VTE) has a high prevalence in patients with multiple comorbidities undergoing complex surgical procedures. Sometimes, extended prophylaxis for VTE with...

Sponsor: Science Valley Research InstituteEnrolling: 1001 location
RECRUITINGNCT06124586

Early Percutaneous Transluminal Angioplasty in Diabetic Foot Syndrome (PTA-DFS)

The planned study is a Randomized Controlled Monocentric Trial, which will provide evidence on whether early angiography in percutaneous transluminal angioplasty (PTA) readiness...

Sponsor: Heinrich-Heine University, DuesseldorfEnrolling: 2001 location

Frequently Asked Questions

There are currently 31 clinical trials for Peripheral Arterial Disease, with 31 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Peripheral Arterial Disease, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Peripheral Arterial Disease, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.