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Pulmonary Arterial Hypertension Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

17 recruiting trials for Pulmonary Arterial Hypertension. Eligibility criteria explained in plain English.

TrialFinderData lists 17 Pulmonary Arterial Hypertension clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 2 is the largest group at 29% (2 studies); the largest phase groups are Phase 2: 2, Phase 3: 2, Phase 4: 1, Phase 1: 1.

Research is led by ChromX Health (1), University of Washington (1), Taichung Veterans General Hospital (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Placebo (drug, 2 trials), followed by Gas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (μGC-PID) system, Valsartan 40 mg.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
17
Total Trials
17
Recruiting Now
2
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT06528418

Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath

The goal of this observational study is to develop an advanced expiratory algorithm model utilizing exhaled breath volatile organic compound (VOC) marker molecules. This model...

Sponsor: ChromX HealthEnrolling: 100001 location
RECRUITINGPhase 2NCT06053580

Repurposing Valsartan May Protect Against Pulmonary Hypertension

This is a Phase 2, single-center, randomized placebo controlled trial of valsartan (an angiotensin receptor blocker) in adults with pulmonary arterial hypertension. The study will...

Sponsor: University of WashingtonEnrolling: 601 location
RECRUITINGNCT06476470

Taiwan Interstitial Lung Disease Multi-center Investigation and Registry

The Taiwan Interstitial Lung Disease (ILD) Multi-center Investigation and Registry aims to evaluate the long-term outcomes of patients with fibrotic interstitial lung disease....

Sponsor: Taichung Veterans General HospitalEnrolling: 100001 location
RECRUITINGPhase 2NCT06351345

129 Xenon Imaging in Patients Treated With Sotatercept

Determine the ability of 129Xe MRI/MRS biomarker signatures to non-invasively monitor pulmonary vascular reverse remodeling induced by sotatercept in pulmonary arterial...

Sponsor: Bastiaan DriehuysEnrolling: 141 location
RECRUITINGNCT07366879

Exercise Intervention as an Adjunct to Medical Therapy in Newly Diagnosed Patients With Pulmonary Arterial Hypertension

The goal of this clinical trial is to learn if an exercise programme started shortly after diagnosis improves the fitness and mental wellbeing of patients with pulmonary...

Sponsor: Golden Jubilee National HospitalEnrolling: 401 location
RECRUITINGNCT06567379

Myocardial Work Evaluation in Patients With PAH

Right ventricular function is a key determinant of survival in patients with pulmonary arterial hypertension, with right heart failure being the leading cause of death. ERS/ESC...

Sponsor: Central Hospital, Nancy, FranceEnrolling: 301 location
RECRUITINGNCT02691689

Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions

Pulmonary arterial hypertension (PAH) in patients with congenital heart disease (CHD) is associated with considerable morbidity and even mortality. Next to environmental risk...

Sponsor: Universitaire Ziekenhuizen KU LeuvenEnrolling: 211 location
RECRUITINGPhase 4NCT06658522

Right Ventricular Compensation With Sotatercept: A Prospective Single Arm Open Label Phase 4 Study to Evaluate the...

Pulmonary arterial hypertension (PAH) is a progressive disease characterized by vascular remodelling resulting in elevated pressures in the pulmonary artery (PA). This elevated...

Sponsor: Amsterdam UMC, location VUmcEnrolling: 201 location
RECRUITINGPhase 1NCT06429930

Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults

This is the second single ascending dose study of L608 in healthy participants and is being conducted to evaluate the safety of L608 with dose level ranging from 15 μg to 30 μg.

Sponsor: Pharmosa Biopharm Inc.Enrolling: 321 location
RECRUITINGPhase 3NCT06350032

Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH

The goal of this clinical trial is to evaluate safety and tolerability of preservative-free parenteral treprostinil in paediatric patients with PAH (PH Group 1) who are below 18...

Sponsor: AOP Orphan Pharmaceuticals AGEnrolling: 205 locations
RECRUITINGPhase 3NCT07365332

An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

This is an adaptive, 2-part, randomized, multicenter, double-blind, placebo-controlled, parallel-group study designed to evaluate the efficacy and safety of IKT-001 in adult...

Sponsor: Inhibikase TherapeuticsEnrolling: 4862 locations
RECRUITINGNCT05368467

National Registry and Cohort Study of Pulmonary Vascular Disease

This is a observational、multicenter, prospective cohort study for patients with pulmonary hypertension (PH). The purposes of this study were to evaluate the etiology、clinical...

Sponsor: Nanjing First Hospital, Nanjing Medical UniversityEnrolling: 100013 locations
RECRUITINGNCT06998329

PulmonAry hyperteNsion DiagnOsis: a National cohoRt reseArch

Understanding Delays in the Diagnosis of Pulmonary Arterial Hypertension and Rare Diseases in Brazil: A Multicenter Observational Study \--- Pulmonary arterial hypertension (PAH)...

Sponsor: University of Sao Paulo General HospitalEnrolling: 1391 location
RECRUITINGNCT04555161

Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

This prospective study is a multi-center early feasibility study assessing the safety and performance of the Aria CV Pulmonary Hypertension System in patients with pulmonary...

Sponsor: Aria CV, IncEnrolling: 3012 locations
RECRUITINGEarly Phase 1NCT05452889

PET Image in PAH Patients

Pulmonary arterial hypertension (PAH) is mortal disease affecting the blood vessels of the lung. Despite its morbid prognosis, PAH is often misdiagnosed or ignored, with an...

Sponsor: Stephen Y. ChanEnrolling: 711 location
RECRUITINGNCT06549452

Mobile Health Intervention to Improve Exercise in Pediatric PH

Children and adults with pulmonary arterial hypertension (PAH) have severely reduced daily activity compared to healthy populations. In adults, investigators recently demonstrated...

Sponsor: Vanderbilt University Medical CenterEnrolling: 501 location
RECRUITINGNCT04278404

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of...

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults...

Sponsor: Duke UniversityEnrolling: 500020 locations

Frequently Asked Questions

There are currently 17 clinical trials for Pulmonary Arterial Hypertension, with 17 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Pulmonary Arterial Hypertension, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 2 Phase 3 trials for Pulmonary Arterial Hypertension, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.