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Refractory Multiple Myeloma Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

8 recruiting trials for Refractory Multiple Myeloma. Eligibility criteria explained in plain English.

TrialFinderData lists 8 Refractory Multiple Myeloma clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 is the largest group at 43% (3 studies); the largest phase groups are Phase 1: 3, Phase 1 / Phase 2: 2, Phase 2: 2.

Research is led by iCell Gene Therapeutics (1), Alliance for Clinical Trials in Oncology (1), David Avigan (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Computed Tomography (procedure, 4 trials), followed by Positron Emission Tomography, Bone Marrow Biopsy.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
8
Total Trials
8
Recruiting Now
0
Phase 3 Trials
8
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 1NCT04162353

BCMA-CD19 cCAR in Multiple Myeloma and Plasmacytoid Lymphoma

This is a phase I, interventional, single arm, open label, treatment study to evaluate the safety and tolerability of BCMA-CD19 cCAR in patients with relapsed and/or refractory...

Sponsor: iCell Gene TherapeuticsEnrolling: 122 locations
RECRUITINGPhase 1 / Phase 2NCT06232044

Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory...

This phase I/II trial tests the safety, side effects, best dose, and effectiveness of iberdomide in combination with belantamab mafodotin and dexamethasone in treating patients...

Sponsor: Alliance for Clinical Trials in OncologyEnrolling: 8820 locations
RECRUITINGPhase 1NCT06799026

A Phase 1 Study of Vaccination With Dendritic Cell (DC)/Multiple Myeloma (MM) Fusions in Combination With Elranatamab...

This research is being done to determine if the combination of the Dendritic Cell (DC)/ Multiple Myeloma (MM) fusion vaccine with elranatamab is safe and effective in treating...

Sponsor: David AviganEnrolling: 252 locations
RECRUITINGPhase 1NCT05020444

TriPRIL CAR T Cells in Multiple Myeloma

This research study involves the study of TriPRIL CAR T Cells for treating people with relapsed or refractory multiple myeloma and to understand the side effects when treated with...

Sponsor: Marcela V. Maus, M.D.,Ph.D.Enrolling: 181 location
RECRUITINGPhase 2NCT05847569

Alternate Doses and Dosing Schedules of Belantamab Mafodotin for Treatment of Triple-Class Refractory Multiple Myeloma

This phase II trial tests alternate doses and dosing schedules of belantamab mafodotin in treating patients with triple-class multiple myeloma that has come back (after a period...

Sponsor: Mayo ClinicEnrolling: 621 location
RECRUITINGPhase 1 / Phase 2NCT07181941

Response-Based Dose Reduction of Linvoseltamab in the Treatment of Relapsed, Refractory, or Triple-Class...

This phase I/II trial evaluates the safety and feasibility of early, response-based dose reduction of linvoseltamab in the treatment of patients multiple myeloma that has come...

Sponsor: Fred Hutchinson Cancer CenterEnrolling: 301 location
RECRUITINGPhase 2NCT06627751

Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma in Patients...

This phase II trial studies how well mezigdomide/carfilzomib/dexamethasone (MeziKD) works in treating patients with multiple myeloma (MM) that has come back after a period of...

Sponsor: Roswell Park Cancer InstituteEnrolling: 281 location
RECRUITINGNCT05053607

Real World Insights During Treatment for Relapsed/Refractory Multiple Myeloma with Isatuximab

This descriptive study aims to evaluate the experience of adults with relapsed or refractory multiple myeloma receiving standard of care isatuximab-irfc through collection of...

Sponsor: Pack HealthEnrolling: 502 locations

Frequently Asked Questions

There are currently 8 clinical trials for Refractory Multiple Myeloma, with 8 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Refractory Multiple Myeloma, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Refractory Multiple Myeloma, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.