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Transthyretin Amyloidosis Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

5 recruiting trials for Transthyretin Amyloidosis. Eligibility criteria explained in plain English.

TrialFinderData lists 5 Transthyretin Amyloidosis clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 2 is the largest group at 50% (1 studies); the largest phase groups are Phase 2: 1, Phase 3: 1.

Research is led by Steen Hvitfeldt Poulsen (1), Oregon Health and Science University (1), AstraZeneca (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is 124I-Evuzamitide (diagnostic_test, 1 trial), followed by Acoramidis, Placebo oral tablet.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
5
Total Trials
5
Recruiting Now
1
Phase 3 Trials
5
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT06291805

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Descriptive cross-sectional study on 100 consecutive ATTRwt-CM patients reflecting all NAC stages aiming primarily to investigate ATTRwt-CM patient's quality of life (QoL)...

Sponsor: Steen Hvitfeldt PoulsenEnrolling: 1201 location
RECRUITINGPhase 2NCT05758493

Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis

This is a single center prospective study evaluating 124I-evuzumitide in patients with systemic amyloidosis. The purpose of this study is to 1) Establish the diagnostic accuracy...

Sponsor: Oregon Health and Science UniversityEnrolling: 1501 location
RECRUITINGNCT07205666

The Eplontersen Pregnancy and Lactation Outcomes Study

The overall objective of this DPSS is to describe the occurrence of pregnancy and maternal complications, adverse effects on the developing fetus and neonate, and adverse effects...

Sponsor: AstraZenecaEnrolling: 101 location
RECRUITINGPhase 3NCT06563895

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a...

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque-like substance that...

Sponsor: Eidos Therapeutics, a BridgeBio companyEnrolling: 58720 locations
RECRUITINGNCT07644325

Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy

Transthyretin amyloidosis (ATTR) is an underdiagnosed condition that can present early as carpal tunnel syndrome, sometimes preceding cardiac involvement by several years. The...

Sponsor: Clinique Saint Jean, FranceEnrolling: 5001 location

Frequently Asked Questions

There are currently 5 clinical trials for Transthyretin Amyloidosis, with 5 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Transthyretin Amyloidosis, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Transthyretin Amyloidosis, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.