Children's National Research Institute
4 clinical trials · 4 recruiting · OTHER
Trials by Children's National Research Institute
RECRUITINGPhase 1NCT07172958
Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)
This is a phase I dose-escalation study to determine the safety and feasibility of autologous CAR-TA T cells (B7-H3 CAR+ T cells administered with DNR-PRAME Tumor Antigen-specific...
Sponsor: Children's National Research InstituteEnrolling: 182 locations
RhabdomyosarcomaEwing SarcomaNeuroblastoma+1
RECRUITINGNCT05099874
Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease
Children with sickle cell disease (SCD) exhibit significantly reduced cognitive functioning (often difficulties with attention) compared to peers and siblings without SCD....
Sponsor: Children's National Research InstituteEnrolling: 201 location
Sickle Cell DiseaseAttention DeficitCognitive Deficit in Attention
RECRUITINGPhase 2NCT06358638
Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody
This multicenter prospective study seeks to determine if daratumumab given, prior to HLA-identical sibling donor transplantation using alemtuzumab, low dose total-body...
Sponsor: Children's National Research InstituteEnrolling: 121 location
Sickle Cell Disease
RECRUITINGNCT06770010
Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease
This is a single site nonrandomized pilot clinical trial of the feasibility, acceptability, and efficacy of a combination treatment involving digital Cogmed working memory skills...
Sponsor: Children's National Research InstituteEnrolling: 501 location
Sickle Cell Disease