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M.D. Anderson Cancer Center

44 clinical trials · 44 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by M.D. Anderson Cancer Center

RECRUITINGPhase 2 / Phase 3NCT05766891

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery

To hypnosedation alone given before and during surgery on reducing opioid use after surgery compared to standard general anesthesia given alone or with hypnosedation.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 2251 location
Breast Cancer
RECRUITINGPhase 1NCT03025256

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

This phase I/Ib trial studies the side effects and best dose of intrathecal nivolumab, and how well it works in combination with intravenous nivolumab in treating patients with...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 751 location
Acral Lentiginous MelanomaCentral Nervous System MelanomaClinical Stage IV Cutaneous Melanoma AJCC v8+7
RECRUITINGNCT07164456

Together Stronger: A Family-centered Lifestyle Intervention for Black Prostate Cancer Survivors and Their Caregivers

To establish the efficacy of the family-centered intervention in improving healthy lifestyle behaviors (MVPA and overall diet quality), as well as physical functioning, QoL, and...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 6481 location
Family CenteredBlack EthnicityProstate Cancer Survivors
RECRUITINGPhase 2NCT05454488

An Evidence-Based Focal Cryotherapy Protocol for Focal Ablation of Intermediate Risk Prostate Cancer

To learn if using cryotherapy to treat only the part of the prostate known to contain cancer is effective in controlling prostate cancer

Sponsor: M.D. Anderson Cancer CenterEnrolling: 301 location
Prostate Cancer
RECRUITINGNCT06878131

Precision-MRD: Prospective Observational Study of Biomarker-directed Systemic Therapy for Colorectal Cancer Patients...

The goal of this clinical research study is to learn about the effects of biomarkertargeted therapy on ctDNA in patrticipants with CRC and MRD. This is an observational study....

Sponsor: M.D. Anderson Cancer CenterEnrolling: 401 location
Colorectal Cancer
RECRUITINGNCT06036810

Spanish Decision Tool for Ovarian Cancer Maintenance Therapy

To develop a shared decision-making (SDM) tool to help Spanish-speaking patients make decisions about their maintenance therapy

Sponsor: M.D. Anderson Cancer CenterEnrolling: 701 location
Ovarian Cancer
RECRUITINGPhase 2NCT06548789

Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in...

To Determine the feasibility, compliance and adherence to PreFED intervention in resectable melanoma patients initiating neoadjuvant Ipi/Nivo.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 351 location
Melanoma
RECRUITINGPhase 2NCT06466434

Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in...

To learn about the possible effects of a prebiotic food-enriched diet (PreFED) targeting the gut microbiome in participants with melanoma who are starting immune checkpoint...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 751 location
Unresectable Melanoma
RECRUITINGPhase 1NCT03819296

Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer

This trial studies the role of the gut microbiome and effectiveness of a fecal transplant on medication-induced gastrointestinal (GI) complications in patients with melanoma or...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 8001 location
Clinical Stage 0 Cutaneous Melanoma AJCC v8Clinical Stage I Cutaneous Melanoma AJCC v8Clinical Stage IA Cutaneous Melanoma AJCC v8+41
RECRUITINGPhase 2NCT04771520

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

This phase II trial studies the effect of avapritinib in treating malignant solid tumors that have a genetic change (mutation) in CKIT or PDGFRA and have spread to nearby tissue...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 501 location
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+26
RECRUITINGNCT04751396

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for...

This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who receive or will receive...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 1251 location
Ankylosing SpondylitisAutoimmune DiseaseCrohn Disease+10
RECRUITINGPhase 1NCT06545682

Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)

To find a recommended dose of the combination of alpelisib and pembrolizumab that can be given to patients with metastatic breast cancer or melanoma.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 501 location
Melanoma (Skin Cancer)Breast CancerBrain Metastasases
RECRUITINGPhase 2NCT04594187

Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma

This phase II trial seeks to determine the role of nodal radiation therapy after sentinel lymph node biopsy (SLNB) for patients with high risk sentinel lymph node positive...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 1683 locations
Melanoma
RECRUITINGNCT05011045

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

This study assesses neurocognitive outcomes after receiving radiation therapy to the brain (whole brain radiation therapy) in patients with blood cancers (hematologic...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 1001 location
Central Nervous System LymphomaHematopoietic and Lymphoid Cell NeoplasmLeukemia+3
RECRUITINGPhase 2NCT06967610

Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With...

To learn if the drug combination pirtobrutinib, venetoclax, and obinutuzumab can help to control relapsed CLL/SLL.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 401 location
Chronic Lymphocytic LeukemiaSmall Lymphocytic Leukemia (SLL)
RECRUITINGPhase 2NCT00801489

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating...

This phase II trial studies the side effects and how well fludarabine phosphate, cytarabine, filgrastim-sndz, gemtuzumab ozogamicin, and idarubicin hydrochloride work in treating...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 2701 location
Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1+7
RECRUITINGPhase 2NCT03383575

Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

This phase II trial studies the side effects and how well azacitidine and enasidenib work in treating patients with IDH2-mutant myelodysplastic syndrome. Azacitidine and...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 633 locations
Acute Myeloid LeukemiaBlasts 20-30 Percent of Bone Marrow Nucleated CellsChronic Myelomonocytic Leukemia+4
RECRUITINGPhase 2NCT02727803

Personalized NK Cell Therapy in CBT

This phase II clinical trial studies how well personalized natural killer (NK) cell therapy works after chemotherapy and umbilical cord blood transplant in treating patients with...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 1001 location
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Lymphoblastic Leukemia+23
RECRUITINGNCT07186556

Cancer-related Fatigue and Its Biological Contributors in Adolescent and Young Adult Brain Tumor Survivors: Effects of...

The goal of this research study is to learn about the effects of the RISE-YA intervention on cancer-related fatigue in young adults who are brain cancer survivors.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 751 location
CancerFatigueBrain Tumor Adult
RECRUITINGPhase 2NCT07053033

Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR...

standard paradigm for management of patients who present with concern for recurrence of brain metastases following initial stereotactic radiosurgery (SRS).

Sponsor: M.D. Anderson Cancer CenterEnrolling: 1551 location
Brain Metastases
RECRUITINGNCT04988009

Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology

This study evaluates patient perceptions around quality of care through telemedicine in neuro-oncology. Studying questionnaires related to perceptions quality of care through...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 2001 location
Central Nervous System NeoplasmLeptomeningeal NeoplasmMetastatic Malignant Neoplasm in the Brain+1
RECRUITINGPhase 1 / Phase 2NCT05039632

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy...

This phase I/II trial studies the side effects and possible benefits of NBTXR3, radiation therapy, Anti PD-1 / PD-L1 in treating patients with solid tumor that has spread to the...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 401 location
Advanced Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the LiverMetastatic Malignant Neoplasm in the Lung+1
RECRUITINGPhase 2NCT06940518

Phase II Trial of Ivonescimab in Previously Treated Patients With Advanced Clear Cell Renal Cell Carcinoma

To learn if ivonescimab can help to control previously treated, locally advanced or metastatic ccRCC.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 401 location
IvonescimabClear Cell Renal Carcinoma
RECRUITINGPhase 2NCT06004336

A Randomized Trial of Maintenance Systemic Therapy After Radiation for Oligometastatic Renal Cell Carcinoma (ASTROs)

To learn if adding 1 year of therapy with pembrolizumab can help to continue to control RCC after radiation therapy.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 1441 location
Oligometastatic Renal Cell Carcinoma
RECRUITINGPhase 1 / Phase 2NCT06434350

Enfortumab Vedotin With Radiation for Locally Advanced Bladder Cancer (CONSOLIDATE)

To learn if the combination of enfortumab vedotin plus radiation therapy could help to control the disease.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 411 location
Advanced Bladder Cancer
RECRUITINGNCT07218315

Nanosecond Pulsed Field Ablation in the Management of T1N0M0 Papillary Thyroid Carcinoma

This study is to evaluate the effectiveness of nsPFA in treating papillary thyroid microcarcinoma. T

Sponsor: M.D. Anderson Cancer CenterEnrolling: 152 locations
Thyroid Carcinoma
RECRUITINGNCT06507878

Global Real World Data in Patients With Advanced Thyroid Cancer on Standard of Care and Specialized Interventions-...

The goal of this clinical research study is to learn about the barriers in the real world to accessing treatments for ATC. And to learn about how patients with ATC tolerate and...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 4591 location
Thyroid Cancer
RECRUITINGPhase 1NCT03093909

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Any time the words "you," "your," "I," or "me" appear, it is meant to apply to the potential participant. The goal of this clinical research study is to find the highest...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 441 location
Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7
RECRUITINGNCT04693377

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME...

This trial compares cryoablation combined with stereotactic body radiation therapy to stereotactic body radiation therapy alone to see how well they work in treating patients with...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 401 location
Castration-Resistant Prostate CarcinomaMetastatic Colorectal CarcinomaMetastatic Malignant Neoplasm in the Bone+15
RECRUITINGPhase 2NCT06959511

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

To look at the effectiveness of zanzalintinib, followed by surgery, in treating advanced thyroid cancer. The safety of this treatment will also be studied.

Sponsor: M.D. Anderson Cancer CenterEnrolling: 451 location
Neoadjuvant TreatmentThyroid Cancer

Showing 30 of 44 trials.