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RECRUITINGPhase 2INTERVENTIONAL

Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. These papers have been published and available through PubMed. Additional research is ongoing, with examination of DISE findings, comparison to other evaluation techniques, and the association between DISE findings and surgical outcomes.

Who May Be Eligible (Plain English)

Who May Qualify: - Adult patients with OSA considering surgical treatment Who Should NOT Join This Trial: - Minors - Pregnant women - Patients unable to provide willing to sign a consent form in English themselves - Prisoners - Allergy to propofol, soybean oil, egg lecithin or glycerol - Other contraindication to use of propofol (decision of anesthesiologist or otolaryngologist.) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Adult patients with OSA considering surgical treatment Exclusion Criteria: * Minors * Pregnant women * Patients unable to provide informed consent in English themselves * Prisoners * Allergy to propofol, soybean oil, egg lecithin or glycerol * Other contraindication to use of propofol (decision of anesthesiologist or otolaryngologist.)

Treatments Being Tested

DRUG

Propofol sedation

Patients receive an intravenous propofol infusion titrated to reach a target level of sedation, sleep with arousability to verbal stimuli.

Locations (1)

UCLA Santa Monica Medical Center
Santa Monica, California, United States