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RECRUITINGOBSERVATIONAL

Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The purpose of this feasibility study is to determine if a new emerging technology called photoacoustic tomography (PAT) can be adapted for use in humans for the detection of chronic rheumatoid arthritis.

Who May Be Eligible (Plain English)

Who May Qualify: - Men and women 18 years of age or older can participate in this study. - Patients can participate in this study if they have had rheumatoid arthritis for more than 2 years and their rheumatologist has referred them to this study. - Patients can participate as a healthy volunteer with a known history of rheumatoid arthritis. Who Should NOT Join This Trial: - Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator. - Pregnant patients. - Patients who is claustrophobic. - Patients with impaired renal function cannot participate in this study such as elevate creatinine clearance, patients on kidney dialysis etc. - Patients with shock hypotension or unstable low blood pressure. - Patients with Rhabdomyolysis. - Patients who have had a contrast enhanced (with gadolinium) MRA (magnetic resonance angiography)/ or MRI within the last 3 months. (Contrast is a medication injected into a vein during a imaging examination that helps produce clearer images/pictures). Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Men and women 18 years of age or older can participate in this study. * Patients can participate in this study if they have had rheumatoid arthritis for more than 2 years and their rheumatologist has referred them to this study. * Patients can participate as a healthy volunteer with a known history of rheumatoid arthritis. Exclusion Criteria: * Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator. * Pregnant patients. * Patients who is claustrophobic. * Patients with impaired renal function cannot participate in this study such as elevate creatinine clearance, patients on kidney dialysis etc. * Patients with shock hypotension or unstable low blood pressure. * Patients with Rhabdomyolysis. * Patients who have had a contrast enhanced (with gadolinium) MRA (magnetic resonance angiography)/ or MRI within the last 3 months. (Contrast is a medication injected into a vein during a imaging examination that helps produce clearer images/pictures).

Treatments Being Tested

PROCEDURE

Laser Based Photoacoustic Tomography, MRI, Ultrasound

Healthy subjects will have scans on finger joints with any of the scanning methods described above.

PROCEDURE

laser based photoacoustic tomography, MRI, ultrasound

Subjects with arthritis will have scans on finger joints with any of the scanning methods described above.

Locations (1)

Universtity of Michigan Health System
Ann Arbor, Michigan, United States