Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

Who May Qualify: - Prostate cancer treated primarily with open, laparoscopic or robotically assisted prostatectomy. - Maximum PSA value of 20 ng/ml. Who Should NOT Join This Trial: - Evidence of distant metastasis (M1). - Prior systemic chemotherapy for any reason. - Previous irradiation to the pelvis that would compromise the ability to deliver the prescribed study treatment. - Active inflammatory bowel disease (Crohn's disease, diverticulitis or ulcerative colitis) affecting the rectum. (Non-active diverticulitis and Crohn's disease not affecting the rectum are allowed). - History of hip replacement. - Prior or concurrent cancer, other than non-melanomatous skin cancer, unless disease free for at least 5 years. - Taking Saw Palmetto or methotrexate and unable or unwilling to discontinue its use during radiation. Always talk to your doctor about whether this trial is right for you.