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RECRUITINGINTERVENTIONAL

Clinical Outcomes in Pediatric Obsessive-Compulsive Disorder

Clinical Outcomes Following Group-based Family Cognitive-Behaviour Therapy in Pediatric Obsessive-Compulsive Disorder (OCD)

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Obsessive-Compulsive Disorder (OCD) is a common neuropsychiatric illness beginning in childhood. Effective OCD treatments include cognitive-behaviour therapy (CBT) and medications but access to treatment is difficult and does not systematically include parents. The investigators will evaluate clinical and neural effects of Group-based Family CBT (GF-CBT), via a case-control study including: Group 1 - OCD cases receiving GF-CBT (N=90); Group 2 - OCD waitlist cases (N=90). Effects will be measured between baseline and completion of 12 GF-CBT sessions: comparing OCD severity and functioning changes between Groups 1 and 2.

Who May Be Eligible (Plain English)

Who May Qualify: - Male or female, aged 5-18 years old - Ability of subject and parent to provide informed assent/consent - English-speaking - Current DSM IV-TR Axis I diagnosis of childhood-onset OCD; Moderate to severe OCD (CY-BOCS≥16/40) Who Should NOT Join This Trial: - Current diagnosis of bipolar disorder, psychosis, mental retardation or pervasive developmental disorder (e.g., autism), and current or past substance dependence/abuse Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Male or female, aged 5-18 years old * Ability of subject and parent to provide informed assent/consent * English-speaking * Current DSM IV-TR Axis I diagnosis of childhood-onset OCD; Moderate to severe OCD (CY-BOCS≥16/40) Exclusion Criteria: * Current diagnosis of bipolar disorder, psychosis, mental retardation or pervasive developmental disorder (e.g., autism), and current or past substance dependence/abuse

Treatments Being Tested

BEHAVIORAL

Group-based family cognitive-behavioural therapy

Baseline and post-12 sessions

OTHER

Waitlist

Baseline and post-12 sessions

Locations (1)

BC Children's Hospital Research Institute
Vancouver, British Columbia, Canada