RECRUITINGOBSERVATIONAL
Eye Pressure Lowering Surgery
Observational Study of Ocular Blood Flow Pre- and Post- Glaucoma Surgery Using Functional and Structural Optical Coherence Tomography
About This Trial
The purpose of this study is to determine if lowering the pressure inside the eye improves blood flow to the eye.
Who May Be Eligible (Plain English)
Who May Qualify:
- Subjects diagnosed with perimetric open angle glaucoma or chronic angle closure glaucoma.
- Subjects scheduled to undergo trabeculectomy or tube shunt surgery
Who Should NOT Join This Trial:
- Best-corrected visual acuity less than 20/40
- Age \< 18 or \>85 years
- Refractive error of \> +3.00 D or \< -7.00 D
- Previous vision correction surgery such as Laser-Assisted in situ Keratomileusis (LASIK) or Photorefractive Keratectomy (PRK)
- Previous intraocular surgery except for uncomplicated cataract extraction with posterior chamber intraocular lens implantation
- Diabetic retinopathy
- History of heart failure, myocardial infarction, transient ischemic attack or stroke
- Other diseases that may cause VF loss or optic disc abnormalities
- Inability to clinically view or photograph the optic discs due to media opacity or poorly dilating pupil
- Inability to perform reliably on automated VF testing
- Life-threatening or debilitating illness making it unlikely patient will successfully complete the study.
- Refusal of willing to sign a consent form or of commitment to the full length of the study
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Subjects diagnosed with perimetric open angle glaucoma or chronic angle closure glaucoma.
* Subjects scheduled to undergo trabeculectomy or tube shunt surgery
Exclusion Criteria:
* Best-corrected visual acuity less than 20/40
* Age \< 18 or \>85 years
* Refractive error of \> +3.00 D or \< -7.00 D
* Previous vision correction surgery such as Laser-Assisted in situ Keratomileusis (LASIK) or Photorefractive Keratectomy (PRK)
* Previous intraocular surgery except for uncomplicated cataract extraction with posterior chamber intraocular lens implantation
* Diabetic retinopathy
* History of heart failure, myocardial infarction, transient ischemic attack or stroke
* Other diseases that may cause VF loss or optic disc abnormalities
* Inability to clinically view or photograph the optic discs due to media opacity or poorly dilating pupil
* Inability to perform reliably on automated VF testing
* Life-threatening or debilitating illness making it unlikely patient will successfully complete the study.
* Refusal of informed consent or of commitment to the full length of the study
Locations (1)
OHSU
Portland, Oregon, United States