RECRUITINGINTERVENTIONAL
Physical Activity Program for Reducing Blood Pressure in Sleep Apnea Patients With Resistant Hypertension
Comparison of Standard Treatment by Continuous Positive Airway Pressure (CPAP) and CPAP Combined to a Physical Activity Program for Reducing Blood Pressure in Sleep Apnea Patients With Resistant Hypertension: RAP Randomized Controlled Trial
About This Trial
Investigators hypothesize that CPAP treatment for suppressing OSAS in combination with a physical activity program will optimize 24-hour blood pressure control in patients with OSA-related resistant hypertension.
Who May Be Eligible (Plain English)
Who May Qualify:
- Patient with an obstructive sleep apnea (apnea-hypopnea index \> or equal to 15)
- Patient with resistant hypertension uncontrolled by 3 or more antihypertensive agents
- Ambulatory patient
Who Should NOT Join This Trial:
- Acute hepatic failure, biliary cirrhosis, cholestasis
- Acute hypertension (SBP\>= 180 mmHg and/or DBP \>= 110 mmHg)
- Contraindication to CPAP treatment
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Patient with an obstructive sleep apnea (apnea-hypopnea index \> or equal to 15)
* Patient with resistant hypertension uncontrolled by 3 or more antihypertensive agents
* Ambulatory patient
Exclusion Criteria:
* Acute hepatic failure, biliary cirrhosis, cholestasis
* Acute hypertension (SBP\>= 180 mmHg and/or DBP \>= 110 mmHg)
* Contraindication to CPAP treatment
Treatments Being Tested
OTHER
Physical activity
Physical activity will carry out 3 times per week during 12 weeks for intervention arm
Locations (5)
Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ)
Québec, Canada
Hopital Universitaire de Grenoble
La Tronche, France
Clinique Pasteur
Toulouse, France
Hopitaux Universitaires de Genève
Geneva, Switzerland
Centre Hospitalier Universitaire Vaudois
Lausanne, Switzerland