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RECRUITINGOBSERVATIONAL

OCT Angiography in Wet AMD

Optical Coherence Tomography Angiography in Neovascular Age-related Macular Degeneration

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. diagnose the presence of new blood vessels in wet age-related macular degeneration (AMD) 2. evaluate patients undergoing treatment for wet AMD 3. determine if reduced flow to the choroid is a risk factor for developing wet AMD.

Who May Be Eligible (Plain English)

Inclusion Criteria (Groups with wet AMD): - Adults aged 50 and older with clinical findings of treatment-naïve (never treated) neovascular AMD with active new blood vessel growth confirmed by clinical testing will be considered Inclusion Criteria (Group with healthy eyes) - No evidence of retinal disease - Refractive error greater than +3.00 diopters or -7.00 diopters (glasses Rx) - No recent eye surgery in the last 4 months - No significant cataract to interfere with the quality of the imaging Exclusion Criteria (All Groups): - Inability to give willing to sign a consent form - Significant kidney disease - Blood pressure greater than 180/110 - Previous macular laser treatment - Inability to maintain stable fixation during OCT imaging - Visual acuity worse than 20/200 Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria (Groups with wet AMD): * Adults aged 50 and older with clinical findings of treatment-naïve (never treated) neovascular AMD with active new blood vessel growth confirmed by clinical testing will be considered Inclusion Criteria (Group with healthy eyes) * No evidence of retinal disease * Refractive error greater than +3.00 diopters or -7.00 diopters (glasses Rx) * No recent eye surgery in the last 4 months * No significant cataract to interfere with the quality of the imaging Exclusion Criteria (All Groups): * Inability to give informed consent * Significant kidney disease * Blood pressure greater than 180/110 * Previous macular laser treatment * Inability to maintain stable fixation during OCT imaging * Visual acuity worse than 20/200

Treatments Being Tested

DEVICE

Optical Coherence Tomography

Locations (1)

Casey Eye Institute, Oregon Health & Science University
Portland, Oregon, United States