RECRUITINGOBSERVATIONAL
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
About This Trial
Pheochromocytomas and paragangliomas are neural crest-derived tumors of the nervous system that are often inherited and genetically heterogeneous. Genetic screening is recommended for patients and their relatives, and can guide clinical decisions. However, a mutation is not found in all cases. The aims of this proposal are to: 1) to map gene(s) involved in pheochromocytoma, and 2) identify genotype-phenotype correlations in patients with pheochromocytoma/paraganglioma of various genetic origins.
Who May Be Eligible (Plain English)
Who May Qualify:
- diagnosis of pheochromocytoma and or paraganglioma
- family member with diagnosis of pheochromocytoma and or paraganglioma
- diagnosis of a pheochromocytoma- and or paraganglioma-associated condition
- family member with diagnosis of a pheochromocytoma- and or paraganglioma-associated condition
Who Should NOT Join This Trial:
- unconfirmed diagnosis of pheochromocytoma and/or paraganglioma or associated condition
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* diagnosis of pheochromocytoma and or paraganglioma
* family member with diagnosis of pheochromocytoma and or paraganglioma
* diagnosis of a pheochromocytoma- and or paraganglioma-associated condition
* family member with diagnosis of a pheochromocytoma- and or paraganglioma-associated condition
Exclusion Criteria:
* unconfirmed diagnosis of pheochromocytoma and/or paraganglioma or associated condition
Treatments Being Tested
GENETIC
Genetic screening
Germline and/or tumor samples will be screened for mutations
Locations (1)
University of Texas Health Science Center
San Antonio, Texas, United States