RECRUITINGOBSERVATIONAL

Surveillance of Patients With Precancerous Lesions of the Stomach

Surveillance Strategies of Patients With Precancerous Conditions and Lesions in the Stomach

About This Trial

The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals. Implementing risk stratification only high risk individuals will be offered and performed endoscopic surveillance.

Who May Be Eligible (Plain English)

Who May Qualify: Patients undergoing upper endoscopy Motivation to participate in the study Signed consent Who Should NOT Join This Trial: Known gastric cancer Unwillingness or inability to co-operate Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: Patients undergoing upper endoscopy Motivation to participate in the study Signed consent Exclusion Criteria: Known gastric cancer Unwillingness or inability to co-operate

Treatments Being Tested

PROCEDURE

Upper endoscopy with biopsies

Upper endoscopy with proper biopsy work-up will be used for identification and stratification of gastric lesions as well as acquisition of biopsies for histopathological examination, including H.pylori detection

PROCEDURE

Plasma/serum sampling

Plasma/serum sampling will be used to obtain information for group stratification, e.g. H.pylori status determination, serum biomarkers

PROCEDURE

Biopsies for gastric microbiota

During upper endoscopy biopsies for gastric microbiota analysis will be obtained

PROCEDURE

Faecal sample acquisition

Faecal samples will be obtained for faecal occult blood testing as well as microbiota analysis

Locations (1)

University of Latvia

Riga, Latvia