Immune Responses in Health Care Personnel

Who May Qualify: - Members of health care or laboratory personnel in HUS having decided to take the seasonal influenza vaccination by the routine occupational health care service - General good health as established by or volunteer's own statement - Written willing to sign a consent form - Presumably able and willing to participate in the study during the starting influenza season Who Should NOT Join This Trial: - Any confirmed or suspected immunosuppressive or immunodeficient condition, including human weakened immune system virus (HIV) infection. - Administration (longer than 14 days) of immunosuppressants or other immune- modifying drugs within 6 months before the vaccination; oral corticosteroids in dosages of 20 mg/day or more prednisolone or equivalent are excluded; inhaled or topical steroids are allowed. - Pregnancy or lactation - Acute disease at the time of enrolment (defined as the presence of a moderate or severe illness with or without fever) - Contraindication for influenza vaccination - Any other criteria which, in the investigator's or dedicated study staff member's opinion, would compromise the ability of a subject to participate in the study, a subject's well-being, or the outcome of the study Always talk to your doctor about whether this trial is right for you.