RECRUITINGOBSERVATIONAL

Multi-scale Analysis of Physiological Brain Networks

Multi-scale Analysis of Physiological and Pathological Brain Networks by Simultaneous EEG-MEG-SEEG Recordings

About This Trial

The SEEG implantation is performed on purely clinical criteria for preoperative diagnosis. Magnetoencephalography and EEG are purely passive techniques that do not involve any additional risk. This project is a continuation of an existing project in which it was demonstrated the feasibility of simultaneous SEEG and MEG/EEG recordings.

Who May Be Eligible (Plain English)

Who May Qualify: - Inclusion criteria for patients - Patients for whom intracerebral electrode implantation is in progress as part of the pre-surgical evaluation of their drug-resistant partial epilepsy. - Patient informed, expressing his non-opposition (or legal representative (s), affiliated to a social security scheme - The medical examination is carried out as part of the medical follow-up of these patients - Inclusion criteria for control subjects • Informed subject, expressing his non-opposition or legal representative, affiliated to a social security scheme - Who Should NOT Join This Trial: Minors under 12 years - Pregnant or lactating women, - The adults under guardianship or under the protection of justice - Non-beneficiaries of a social security scheme - Persons deprived of their liberty by a judicial or administrative decision - Absence of willing to sign a consent form Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Inclusion criteria for patients * Patients for whom intracerebral electrode implantation is in progress as part of the pre-surgical evaluation of their drug-resistant partial epilepsy. * Patient informed, expressing his non-opposition (or legal representative (s), affiliated to a social security scheme * The medical examination is carried out as part of the medical follow-up of these patients * Inclusion criteria for control subjects • Informed subject, expressing his non-opposition or legal representative, affiliated to a social security scheme * Exclusion Criteria: Minors under 12 years * Pregnant or lactating women, * The adults under guardianship or under the protection of justice * Non-beneficiaries of a social security scheme * Persons deprived of their liberty by a judicial or administrative decision * Absence of informed consent

Treatments Being Tested

OTHER

Multi-scale analysis of physiological brain networks

It will be simultaneously record the surface EEG, the MEG and in patients only the intracerebral EEG (SEEG). In the case of SEEG with micro contacts, these additional signals will also be recorded in parallel and will provide greater sensitivity to high frequency activities. The physiological networks will be studied in patients thanks to stimulations (external or intracerebral) carried out within the framework of the functional cartography, and the pathological networks thanks to measures in state of rest. For external stimulation protocols, it will be constitute a reference base in MEG and EEG alone (non-invasive) on control subjects.

Locations (1)

Assistance Publique Hôpitaux de Marseille

Marseille, France