RECRUITINGPhase 3INTERVENTIONAL
Pantoprazole in Cisplatin Nephrotoxicity
Possible Protective Effect of Pantoprazole in Cisplatin Induced Nephrotoxicity in Patients With Head and Neck Cancer
About This Trial
Pantoprazole in Cisplatin Nephrotoxicity
Who May Be Eligible (Plain English)
Who May Qualify:
- Patients with head and neck cancer
Who Should NOT Join This Trial:
- GFR less than 59.
- DM
- Elevated liver enzymes more than 3 fold.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Patients with head and neck cancer
Exclusion Criteria:
* GFR less than 59.
* DM
* Elevated liver enzymes more than 3 fold.
Treatments Being Tested
DRUG
Pantoprazole low dose
Pantoprazole 0.6 mg/kg
DRUG
Pantoprazole high dose
Pantoprazole 1.6 mg\\kg
OTHER
Standard hydration
Standard hydration alone
DRUG
Cisplatin
Cisplatin
Locations (1)
Sherief Abd-Elsalam
Tanta, Egypt