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RECRUITINGINTERVENTIONAL

COMPuter-assisted Self-training to Improve EXecutive Function

Computer-Assisted Self-Training to Improve Executive Function Versus Unspecific Training in Patients After Stroke, Cardiac Arrest or in Parkinson's Disease: a Randomized Controlled Trial

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease. The effect of specialized CBCR is compared to generally cognitively stimulating activities on a computer

Who May Be Eligible (Plain English)

Who May Qualify: - A diagnose of stroke, cardiac arrest or Parkinson's disease. - Aged 18 years or older. - Impaired working memory measured with CABPad working memory test, cut off for inclusion: 5 symbols or less backwards - Computer and internet access at home. - Providing willing to sign a consent form. Inclusion criteria specific for stroke - Inclusion within 6 months post-stroke - Stroke confirmed by clinical findings and imaging, both AIS and ICH is allowed. - Initial stroke severity \>/= NIHSS 3. Inclusion criteria specific for cardiac arrest • Inclusion within 6 months post ictus. Inclusion criteria specific for Parkinson's disease - Clinical diagnosis of PD. - Anti-parkinsonian medical treatment (dopaminergic or other). Who Should NOT Join This Trial: - willing to sign a consent form not provided - Other neurological or psychiatric disease which is expected to influence the patient's ability to participate in the trial according to the investigator - Not able to participate according to investigator Exclusion criteria specific for stroke - Patients with massive anosognosia for executive dysfunction or patients with no subjective feeling of executive dysfunction (Patient sustains total denial of executive symptoms over time) - Patients with severe aphasia, in which it is unclear whether the patient's performance on a neuropsychological test-battery is due to aphasia and not executive dysfunction. Exclusion criteria specific for cardiac arrest • None Exclusion criteria specific for PD • Diagnosis of PD Dementia according to the MDS PD Dementia criteria Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * A diagnose of stroke, cardiac arrest or Parkinson's disease. * Aged 18 years or older. * Impaired working memory measured with CABPad working memory test, cut off for inclusion: 5 symbols or less backwards * Computer and internet access at home. * Providing informed consent. Inclusion criteria specific for stroke * Inclusion within 6 months post-stroke * Stroke confirmed by clinical findings and imaging, both AIS and ICH is allowed. * Initial stroke severity \>/= NIHSS 3. Inclusion criteria specific for cardiac arrest • Inclusion within 6 months post ictus. Inclusion criteria specific for Parkinson's disease * Clinical diagnosis of PD. * Anti-parkinsonian medical treatment (dopaminergic or other). Exclusion Criteria: * Informed consent not provided * Other neurological or psychiatric disease which is expected to influence the patient's ability to participate in the trial according to the investigator * Not able to participate according to investigator Exclusion criteria specific for stroke * Patients with massive anosognosia for executive dysfunction or patients with no subjective feeling of executive dysfunction (Patient sustains total denial of executive symptoms over time) * Patients with severe aphasia, in which it is unclear whether the patient's performance on a neuropsychological test-battery is due to aphasia and not executive dysfunction. Exclusion criteria specific for cardiac arrest • None Exclusion criteria specific for PD • Diagnosis of PD Dementia according to the MDS PD Dementia criteria

Treatments Being Tested

BEHAVIORAL

Computer-based cognitive rehabilitation (CBCR)

CBCR are software-programmes for computers which are clinically developed for rehabilitation of various cognitive functions.

BEHAVIORAL

General computer-based cognitive stimulation

For this trial we have developed a webpage for general cognitive stimulation, which is designed to provide general computer-based cognitive stimulation.

Locations (2)

Bispebjerg Hospital
Copenhagen, Denmark
Rigshospitalet
Copenhagen, Denmark