RECRUITINGINTERVENTIONAL
Mechanisms of Prediabetic States in Sleep Apnea
About This Trial
The purpose of this study is to better understand how sleep apnea contributes to the development of diabetes.
Who May Be Eligible (Plain English)
Who May Qualify:
- Overweight or obese
- Prediabetic
- Sleep apnea
Who Should NOT Join This Trial:
- Diabetic
- Severe hypertension
- Taking medications that can confound assessments
- Any history of known bleeding disorders
- Any underlying disease likely to limit life span or increase risk of intervention
- Currently pregnant, trying to get pregnant or nursing
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Overweight or obese
* Prediabetic
* Sleep apnea
Exclusion Criteria:
* Diabetic
* Severe hypertension
* Taking medications that can confound assessments
* Any history of known bleeding disorders
* Any underlying disease likely to limit life span or increase risk of intervention
* Currently pregnant, trying to get pregnant or nursing
Treatments Being Tested
DEVICE
Continuous positive airway pressure
Continuous positive airway pressure (CPAP) treatment of obstructive sleep apnea (OSA)
OTHER
Niacin
Suppression of lipolysis by niacin infusion
Locations (1)
University of Chicago
Chicago, Illinois, United States