Community-based Exercise Following Revascularization for PAD

Who May Qualify: - Patients receiving Revascularization for aorto-iliac and/or femoral-popliteal disease in at least one limb - Patients with focal and/or diffuse peripheral artery disease - Bilateral Revascularization patients will also be included - Ability to participate in an exercise program Who Should NOT Join This Trial: - Lower extremity amputation(s) which interfere(s) with walking on the treadmill - Individuals with critical limb ischemia defined by ischemic rest pain or ischemic ulcers/gangrene on the lower extremities - PAD of non-atherosclerotic nature (e.g., fibromuscular dysplasia, irradiation, endofibrosis). - Coronary artery bypass grafts or major surgical procedures within 6 months prior to screening - Individuals whose walking exercise is primarily limited by symptoms of chronic obstructive pulmonary disease, angina, or heart failure - Individuals who have had a myocardial infarction within 3 months prior to screening - Individuals who have had a transient ischemic attack or stroke 3 months prior to screening - Individuals with uncontrolled hypertension (≥180 systolic or ≥100 diastolic resting blood pressure) during screening - Treatment with pentoxifylline or cilostazol for the treatment of claudication 4 weeks prior to screening. Patients can be reconsidered for study inclusion following a 1-month waiting period after previous treatment - Poorly controlled diabetes defined as glycated hemoglobin \>12% - Abnormal results of blood work not conducive to safely participate in an exercise trial (e.g., anemic, electrolyte abnormalities) - Inability to speak English - Other clinically significant cardiovascular, pulmonary, renal, endocrine, hepatic, neurological, psychiatric, immunological, gastrointestinal, hematological, or metabolic disease that is, in the opinion of the study team, not stabilized or may otherwise confound the results of the study Always talk to your doctor about whether this trial is right for you.