RECRUITINGINTERVENTIONAL

Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder

About This Trial

Alcohol use disorder (AUD) is the second highest preventable cause of death in France. Only 3% of patients are prescribed approved drugs for reducing alcohol consumption or maintenance of abstinence. Increasing evidence supports the efficacy of psychotherapies such as cognitive and behavioral therapies (CBT) in AUD. However, some patients are resistant to CBT and the positive effects of CBT could wane over time, resulting in mid- and long-term relapses. Mindfulness practice is increasingly widespread in the United States and its efficacy in various fields appears very promising. The study investigators hypothesize that the Mindfulness Based Relapse Prevention (MBRP) program will be more efficient than a relaxation/meditation without guidance control program in AUD.

Who May Be Eligible (Plain English)

Who May Qualify: - Having a moderate to severe alcohol use disorder according to DSM 5 criteria. - The last drink must have been consumed at most in the last 60 days before the pre-inclusion visit. The patient must have had at least 1 HDD during the last drinking period Who Should NOT Join This Trial: - Severe depression (Beck Depression Inventory\> 30) - Schizophrenic disorder, - Current maniac or hypomaniac episode, - Patient with dementia or severe cognitive impairment that would prevent him/her from following the course of a session, as judged by the clinician. - Insufficient French understanding to complete the questionnaires - Pregnant or breastfeeding woman - Absence of social security regimen - Other mindfulness-based structured therapies - Refusal to sign the written consent. • The patient is under safeguard of justice or state guardianship Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Having a moderate to severe alcohol use disorder according to DSM 5 criteria. * The last drink must have been consumed at most in the last 60 days before the pre-inclusion visit. The patient must have had at least 1 HDD during the last drinking period Exclusion Criteria: * Severe depression (Beck Depression Inventory\> 30) * Schizophrenic disorder, * Current maniac or hypomaniac episode, * Patient with dementia or severe cognitive impairment that would prevent him/her from following the course of a session, as judged by the clinician. * Insufficient French understanding to complete the questionnaires * Pregnant or breastfeeding woman * Absence of social security regimen * Other mindfulness-based structured therapies * Refusal to sign the written consent. • The patient is under safeguard of justice or state guardianship

Treatments Being Tested

BEHAVIORAL

Mindfulness Based Relapse Prevention

7 x 60-120 minute sessions with different themes: Automatic pilot/triggers/relapse/high-risk situations/ mindfulness in daily life. There will be a welcoming time, with a focus on at-home practice and difficulties, a theoretical presentation of new concepts, practical meditation exercises and a debriefing.

BEHAVIORAL

Relaxation/ meditation

7 x 60-120 minute sessions each with a different sound from nature with unguided, closed relaxation group with a maximum of 12 participants

Locations (7)

Ssra Les Eumenides

Angers, France

Hôpital Corentin-Celton

Issy-les-Moulineaux, France

CHU de Nantes

Nantes, France

CHU de Nimes

Nîmes, France

Hopital Fernand Widal

Paris, France

Hopital Des 4 Villes

Sèvres, France

Hopital Paul Brousse

Villejuif, France