Skip to main content
TTrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor.
RECRUITINGOBSERVATIONAL

Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery

Cardiorespiratory Fitness, Inflammatory Biomarkers, and Cognitive Function Patterns During Treatment for Breast Cancer: a Prospective Cohort Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This study will primarily identify longitudinal associations between cardiorespiratory fitness (CRF) and cognitive function pre- (baseline) to post-chemotherapy (\~3 months). This will be a prospective study of 50 BCS. We hypothesize that breast cancer patients undergoing chemotherapy who have higher levels of CRF at baseline will have significantly improved measures of attention, executive function, and memory post-chemotherapy. In addition, the exploratory aims will examine the longitudinal associations between physical activity (PA) and cognitive function from pre- to post-chemotherapy and explore the associations between inflammatory and non-inflammatory biomarkers and CRF with cognitive function.

Who May Be Eligible (Plain English)

Who May Qualify: - 18-65 years old - histologically-confirmed stage I-III breast cancer, but prior to the initiation of chemotherapy (\<1 cycle of adjuvant therapy or neoadjuvant therapy) - no diagnosed major cognitive disorders and uncontrolled comorbidities. Who Should NOT Join This Trial: - received neoadjuvant chemotherapy and scheduled to receive adjuvant chemotherapy - scheduled to receive concurrent radiation therapy with chemotherapy. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * 18-65 years old * histologically-confirmed stage I-III breast cancer, but prior to the initiation of chemotherapy (\<1 cycle of adjuvant therapy or neoadjuvant therapy) * no diagnosed major cognitive disorders and uncontrolled comorbidities. Exclusion Criteria: * received neoadjuvant chemotherapy and scheduled to receive adjuvant chemotherapy * scheduled to receive concurrent radiation therapy with chemotherapy.

Locations (1)

Sunnybrook Health Sciences Centre-Odette Cancer Centre
Toronto, Ontario, Canada