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RECRUITINGINTERVENTIONAL

Endoscopic Cyclophotocoagulation in Normal Tension Glaucoma

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The purpose of this study is to assess whether endoscopic cyclophotocoagulation added to cataract surgery lowers intraocular pressure more than cataract surgery alone in patients with normal tension glaucoma.

Who May Be Eligible (Plain English)

Who May Qualify: - Signed willing to sign a consent form - Normal Tension Glaucoma with typical nerve fiber layer defects in red-free photographs and/or optical coherence tomography (OCT) and possible equivalent visual field defects, IOP never more than 21 mmHg, and open anterior chamber angle - Glaucoma stable with current medication assessed by a glaucoma specialist - Clinically significant cataract Who Should NOT Join This Trial: - Secondary Glaucoma e.g. due to previous injury or uveitis - Exfoliation syndrome - Pigment dispersion syndrome - Previous transscleral or endoscopic cyclophotocoagulation - Previous other glaucoma surgery - Cataract due to eye injury or congenital cataract - Zonular weakness due to Marfan syndrome or other - Previous retinal detachment - Previous intraocular surgery like vitrectomy and other retinal surgery - Wet age-related macular degeneration - Diabetic retonopathy - Previous corneal transplant or previous refractive surgery - Fuchs' dystrophy and other abnormalities compromising corneal clarity like scars - The patient does not want to participate in the study - The glaucoma progresses on current IOP - The patient does not speak Finnish, Swedish or English - Dementia - Only eye with vision worse than 20/200 or loss of central visual field Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Signed Informed Consent * Normal Tension Glaucoma with typical nerve fiber layer defects in red-free photographs and/or optical coherence tomography (OCT) and possible equivalent visual field defects, IOP never more than 21 mmHg, and open anterior chamber angle * Glaucoma stable with current medication assessed by a glaucoma specialist * Clinically significant cataract Exclusion Criteria: * Secondary Glaucoma e.g. due to previous injury or uveitis * Exfoliation syndrome * Pigment dispersion syndrome * Previous transscleral or endoscopic cyclophotocoagulation * Previous other glaucoma surgery * Cataract due to eye injury or congenital cataract * Zonular weakness due to Marfan syndrome or other * Previous retinal detachment * Previous intraocular surgery like vitrectomy and other retinal surgery * Wet age-related macular degeneration * Diabetic retonopathy * Previous corneal transplant or previous refractive surgery * Fuchs' dystrophy and other abnormalities compromising corneal clarity like scars * The patient does not want to participate in the study * The glaucoma progresses on current IOP * The patient does not speak Finnish, Swedish or English * Dementia * Only eye with vision worse than 20/200 or loss of central visual field

Treatments Being Tested

PROCEDURE

Phaco

phacoemulsification of cataract only

PROCEDURE

Phaco+ECP

Endoscopic cyclophotocoagulation is done in the same procedure as phacoemulsification of cataract

Locations (1)

Helsinki University Hospital
Helsinki, Finland