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RECRUITINGINTERVENTIONAL

Transcranial Magnetic Stimulation (TMS) Study for Adults With Autism Spectrum Disorder (ASD)

Noninvasive Brain Stimulation to Treat Core Social Deficits in Autism Spectrum Disorder

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This is a randomized interventional study designed to evaluate the effects of repetitive Transcranial Magnetic Stimulation (rTMS) on neural and behavioral facets of social cognition in adults with autism spectrum disorder (ASD).

Who May Be Eligible (Plain English)

Who May Qualify: - Individuals between the ages of 18 and 40 years old with typical development or with a diagnosis of autism spectrum disorder. - Individuals able to participate in an EEG and eye-tracking experiment. Who Should NOT Join This Trial: - Participants reporting significant head trauma or serious brain illness. - Participants with major psychiatric illness that would preclude completion of study measures. - Participants with a history of serious medical illness, stroke, seizures, epileptiform EEG abnormalities, or family history of seizures. - Participants taking prescription medications that may affect cognitive processes under study. - Participants who have taken alcohol or recreational drugs within the preceding 24 hours. - Females of known/suspected pregnancy or who test positive on a pregnancy test. - Participants with a history of metalworking or injury by shrapnel or metallic objects are also excluded. - Participants with a history of prior TMS therapy or use of an investigational drug within 12 weeks of visit. - Participants with an IQ (intelligence quotient) below 80. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Individuals between the ages of 18 and 40 years old with typical development or with a diagnosis of autism spectrum disorder. * Individuals able to participate in an EEG and eye-tracking experiment. Exclusion Criteria: * Participants reporting significant head trauma or serious brain illness. * Participants with major psychiatric illness that would preclude completion of study measures. * Participants with a history of serious medical illness, stroke, seizures, epileptiform EEG abnormalities, or family history of seizures. * Participants taking prescription medications that may affect cognitive processes under study. * Participants who have taken alcohol or recreational drugs within the preceding 24 hours. * Females of known/suspected pregnancy or who test positive on a pregnancy test. * Participants with a history of metalworking or injury by shrapnel or metallic objects are also excluded. * Participants with a history of prior TMS therapy or use of an investigational drug within 12 weeks of visit. * Participants with an IQ (intelligence quotient) below 80.

Treatments Being Tested

BEHAVIORAL

Transcranial Magnetic Stimulation (TMS)

Subjects will receive both active and sham TMS in a randomized crossover assignment involving two study sessions

Locations (1)

Yale University Child Study Center
New Haven, Connecticut, United States