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RECRUITINGINTERVENTIONAL

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).

Who May Be Eligible (Plain English)

Who May Qualify: - Patient Inclusion Criteria - Hospitalized patients (age ≥ 18 years) with high-risk AML defined as: - Patients with new diagnosis ≥ 60 years of age - An antecedent hematologic disorder - Therapy related-disease - Relapsed or primary refractory AML - Within five business days of initiating therapy with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen requiring prolonged hospitalization; or b) hypomethylating agents +/- additional agents or modification of this regimen on a clinical trial. - Caregiver Inclusion Criteria - Adult (≥18 years) relative or friend of a participating patient who the patient identifies as living with or has in-person contact with them at least twice per week. Who Should NOT Join This Trial: \- Patient Exclusion Criteria - Patients with a diagnosis of acute promyelocytic leukemia (APML) - Patients with AML receiving supportive care alone - Patients with psychiatric or cognitive conditions which the treating clinicians believe prohibits willing to sign a consent form or compliance with study procedures - Patients seen by a palliative care clinician (MD, DO, APP) during two previous hospitalizations in the six months prior to enrollment - Patients expected to be discharged within 2 days Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Patient Inclusion Criteria * Hospitalized patients (age ≥ 18 years) with high-risk AML defined as: * Patients with new diagnosis ≥ 60 years of age * An antecedent hematologic disorder * Therapy related-disease * Relapsed or primary refractory AML * Within five business days of initiating therapy with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen requiring prolonged hospitalization; or b) hypomethylating agents +/- additional agents or modification of this regimen on a clinical trial. * Caregiver Inclusion Criteria * Adult (≥18 years) relative or friend of a participating patient who the patient identifies as living with or has in-person contact with them at least twice per week. Exclusion Criteria: \- Patient Exclusion Criteria * Patients with a diagnosis of acute promyelocytic leukemia (APML) * Patients with AML receiving supportive care alone * Patients with psychiatric or cognitive conditions which the treating clinicians believe prohibits informed consent or compliance with study procedures * Patients seen by a palliative care clinician (MD, DO, APP) during two previous hospitalizations in the six months prior to enrollment * Patients expected to be discharged within 2 days

Treatments Being Tested

BEHAVIORAL

Specialty Palliative Care

Participants assigned to specialty palliative care will be cared for by both oncology and palliative care clinicians during their hospital stays for AML.

BEHAVIORAL

Primary Palliative Care

Participants assigned primary palliative care will be cared for by oncology clinicians who have been trained in palliative care during the hospital stays for AML.

Locations (20)

University of Alabama - Birmingham
Birmingham, Alabama, United States
Stanford University
Stanford, California, United States
University of Colorado Denver I Anschutz Medical Campus
Denver, Colorado, United States
University of Miami
Miami, Florida, United States
Moffitt Cancer Center
Tampa, Florida, United States
Emory University
Atlanta, Georgia, United States
Northwestern University
Evanston, Illinois, United States
Indiana University
Bloomington, Indiana, United States
Johns Hopkins University
Baltimore, Maryland, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Mayo Clinic
Rochester, Minnesota, United States
University of Rochester
Rochester, New York, United States
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
Duke University
Durham, North Carolina, United States
Ohio State University
Columbus, Ohio, United States
Oregon Health & Science University
Portland, Oregon, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Fred Hutchinson Cancer Center
Seattle, Washington, United States
University of Wisconsin
Madison, Wisconsin, United States