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RECRUITINGINTERVENTIONAL

Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

record fast ripples with novel intracranial electrodes with micro-tetrodes to improve the identification of epileptogenic zone (EZ) and investigate the neuronal circuits underlying brain dynamics associated with epilepsy

Who May Be Eligible (Plain English)

Who May Qualify: - inclusion criteria is determined based on the clinical diagnosis of the refractory epilepsy and the admissibility of the patient for the stereoelectroencephalography (sEEG) procedure Who Should NOT Join This Trial: - severe psychiatric disorders, - severe agitation during their crisis - contraindication for performing an MRI: claustrophobia, a cardiac or neural stimulator, ferromagnetic surgical clips, cochlear implants, intraocular metallic foreign body or in the nervous system, - contraindication to intracerebral investigation (macro-electrodes): ongoing infection, severe associated pathology (cardiac, pulmonary, renal, hepatic), pregnant or nursing women, - anti thrombotic ongoing treatment. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * inclusion criteria is determined based on the clinical diagnosis of the refractory epilepsy and the admissibility of the patient for the stereoelectroencephalography (sEEG) procedure Exclusion Criteria: * severe psychiatric disorders, * severe agitation during their crisis * contraindication for performing an MRI: claustrophobia, a cardiac or neural stimulator, ferromagnetic surgical clips, cochlear implants, intraocular metallic foreign body or in the nervous system, * contraindication to intracerebral investigation (macro-electrodes): ongoing infection, severe associated pathology (cardiac, pulmonary, renal, hepatic), pregnant or nursing women, * anti thrombotic ongoing treatment.

Treatments Being Tested

DEVICE

macro-micro tetrodes for intracranial recording

novel design of tetrode micro electrodes within the standard macro intracranial electrodes used clinically for identification of the epileptogenic zone

Locations (1)

McGill University
Montreal, Quebec, Canada