Fully Automated High-Throughput Quantitative MRI of the Liver

Eligibility Criteria for Substudies 1, 2, 4, 5 Who May Qualify: - Age 18 years or older Who Should NOT Join This Trial: - Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc) - Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening) Eligibility Criteria for Substudy 3 Who May Qualify: - Age 7 years or older - One of: - Known or suspected liver iron overload - Known or suspected elevated liver fat Who Should NOT Join This Trial: - Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc) - Patients requiring intravenous (IV) conscious sedation for imaging are not eligible; patients requiring mild, oral anxiolytics for the MRI will be allowed to participate as long as the following criteria are met: - The subject has their own prescription for the medication. - The willing to sign a consent form process is conducted prior to the self-administration of this medication - They come to the research visit with a driver - Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening) Eligibility Criteria for Substudy 6 Who May Qualify: - Age 7 years or older - Scheduled for a clinical abdominal MRI exam Who Should NOT Join This Trial: - Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc) - Sedation required for MRI - Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening) Always talk to your doctor about whether this trial is right for you.