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RECRUITINGINTERVENTIONAL

Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.

Who May Be Eligible (Plain English)

Who May Qualify: - Mild Cognitive Impairment due to Alzheimer's disease - Dementia with Lewy Bodies - Frontotemporal dementia - Idiopathic normal pressure hydrocephalus (iNPH) Who Should NOT Join This Trial: - History of seizures - Pregnancy - Metal implants in the head (except dental fillings) - Electronic implants (i.e. pace-maker, implanted medical pump) - Age \<18 years Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Mild Cognitive Impairment due to Alzheimer's disease * Dementia with Lewy Bodies * Frontotemporal dementia * Idiopathic normal pressure hydrocephalus (iNPH) Exclusion Criteria: * History of seizures * Pregnancy * Metal implants in the head (except dental fillings) * Electronic implants (i.e. pace-maker, implanted medical pump) * Age \<18 years

Treatments Being Tested

DEVICE

Gamma tACS (40 Hz) over the superior parietal cortex

Single session of gamma tACS (40 Hz) over the superior parietal cortex

Locations (1)

Kuopio University Hospital
Kuopio, Finland