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RECRUITINGINTERVENTIONAL

MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal Photochemotherapy

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The objective of this study is to describe the type of cell death induced by extracorporeal photochemotherapy, depending on the cell type, using a panel of complementary analysis techniques.

Who May Be Eligible (Plain English)

Who May Qualify: - Adult patients - Treated with ECP for at least 1 month, for control of GVHD in hematopoietic cell allograft (acute or chronic GVHD), treatment and control of cellular or humoral rejection in solid organ transplantation (heart, lung, kidney) or in the treatment of cutaneous T-cell lymphoma Who Should NOT Join This Trial: - Subjects with limited legal capacity. - Subjects judged by the investigator to be unlikely to comply with study procedures - Subjects with no social security coverage. - Pregnant women. - Subjects still in the exclusion period of another study, or according to the national registry of clinical trial participants. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Adult patients * Treated with ECP for at least 1 month, for control of GVHD in hematopoietic cell allograft (acute or chronic GVHD), treatment and control of cellular or humoral rejection in solid organ transplantation (heart, lung, kidney) or in the treatment of cutaneous T-cell lymphoma Exclusion Criteria: * Subjects with limited legal capacity. * Subjects judged by the investigator to be unlikely to comply with study procedures * Subjects with no social security coverage. * Pregnant women. * Subjects still in the exclusion period of another study, or according to the national registry of clinical trial participants.

Treatments Being Tested

OTHER

Samples collection

Sampling of 2 samples on the extracorporeal photochemotherapy circuit, before and after sensitization with 8-MOP and UVA irradiation (without additional puncture)

Locations (1)

Centre Hospitalier Universitaire de Besançon
Besançon, France