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RECRUITINGPhase 2INTERVENTIONAL

Cognitive Remediation Intervention to Prepare for Transition of Care

The Cognitive-Remediation of Executive and Adaptive Deficits in Youth (C-READY) Intervention: A Randomized Controlled Trial for Adolescents With Sickle Cell Disease to Prepare for Transition of Care

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Randomized Controlled Trial (RTC) testing the efficacy of a telehealth adaptation of the Cognitive-Remediation of Executive and Adaptive Deficits in Youth (C-READY) intervention to prepare adolescents with sickle cell disease for transition of care.

Who May Be Eligible (Plain English)

Who May Qualify: - Diagnosis of SCD (all genotypes) - Active follow-up at Children's of Alabama Hospital - Ages 10-18 - English-speaking Who Should NOT Join This Trial: - History of seizures or overt stroke - History of Intellectual Disability or Autism Spectrum Disorder - Inability to participate in the MRI scan, such as metal implants, neurostimulators, claustrophobia - Currently on psychotropic medications Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Diagnosis of SCD (all genotypes) * Active follow-up at Children's of Alabama Hospital * Ages 10-18 * English-speaking Exclusion Criteria: * History of seizures or overt stroke * History of Intellectual Disability or Autism Spectrum Disorder * Inability to participate in the MRI scan, such as metal implants, neurostimulators, claustrophobia * Currently on psychotropic medications

Treatments Being Tested

BEHAVIORAL

CREADY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)

Manualized cognitive remediation intervention that includes 1) skills-based remediation (metacognitive training), 2) parent training, and 3) cognitive behavioral approaches. Intervention targets self-management and goal-setting skill building to promote independence in activities necessary for transition of care.

Locations (1)

University of Alabama at Birmingham
Birmingham, Alabama, United States