RECRUITINGOBSERVATIONAL
Global collaboRAtion on CIC-DUX4, BCOR-CCN3, High-grade Undifferentiated Round Cell Sarcoma (URCS) Project
About This Trial
Experimental study with biological material : case series review of clinical and histological data
Who May Be Eligible (Plain English)
Who May Qualify:
- Patients with undifferentiated round cell sarcomas treated from 01 January 1983 and all new patients will be included.
- Clinical and outcome information available.
- Histological slides/formalin-fixed paraffin-embedded tissue tumor blocks from archive available to perform the histology analysis/frozen tissue representative of the tumor available.
Who Should NOT Join This Trial:
- Diagnosis different from undifferentiated round cell sarcomas
- Patient with no clinical or outcome information available
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Patients with undifferentiated round cell sarcomas treated from 01 January 1983 and all new patients will be included.
* Clinical and outcome information available.
* Histological slides/formalin-fixed paraffin-embedded tissue tumor blocks from archive available to perform the histology analysis/frozen tissue representative of the tumor available.
Exclusion Criteria:
* Diagnosis different from undifferentiated round cell sarcomas
* Patient with no clinical or outcome information available
Treatments Being Tested
OTHER
data collection and analysis on Formalin-fixed paraffin embedded tissue and/or frozen tumoral tissue
Formalin-fixed paraffin embedded tissue and/or frozen tumoral tissue of cases negative for all Ewing's sarcoma molecular fusions, will be analyzed for the presence of CIC-DUX4 / BCOR-CCNB3 translocations fusion at each Institution. Treatment, outcome, and prognostic factors will be related with the molecular re-classification.
Locations (1)
IRCCs Istituto Ortopedico Rizzoli
Bologna, BO, Italy