Clinical Study on the Re-irradiation of Lateral Pelvic Recurrences of Gynecological Malignancies

Who May Qualify: - Patients ≥ 18 years of age - Karnofsky Index ≥ 70 - Histological or radiological diagnosis of pelvic and groin recurrence - Contraindications for radical surgery - No other distant progression or stable disease (SD) of known secondarisms (≥6 months) - Previous radiation therapy on pelvis - Distance ≥ 10mm between tumour and close intestinal tract (small intestine), radiologically evaluated - Possibility to perform a surgery to space the intestinal loops, in case of distance \< 10mm - If needed, spacer in biocompatible material (silicon, goretex) or anatomical material (omentum, muscle patch), non-absorbable. - DICOM (Digital Imaging and COmmunications in Medicine) images of the previous treatment plan availability - Written willing to sign a consent form - Patient's ability to understand the characteristics and consequences of the clinical trial Who Should NOT Join This Trial: - Hip prosthesis, metal prostheses or any other condition that prevents adequate imaging to identify the target volume and calculate the dose in the treatment plan - Intestinal infiltration - Bladder infiltration - Vessel infiltration - Previous therapy with anti-angiogenesis drugs - Psychic or other disorders that may prevent willing to sign a consent form - Previous invasive tumor, with the exception of skin cancer (excluding melanoma) unless disease-free for at least 3 years - Spacer in absorbable material (i.e. vycril) - Distance \< 10mm between tumour and close intestinal tract (small intestine), radiologically evaluated - Impossibility to assess MRI Always talk to your doctor about whether this trial is right for you.