RECRUITINGINTERVENTIONAL
Multiparametric Assessment to Investigate Prognostic Factors for Disease Evolution a nd Evolutionary Patterns of Cognitive Status in RRMS
Multiparametric Clinical, Radiological, Neuropsychological, and Neurophysiological Assessment to Investigate Prognostic Factors for Disease Evolution and Treatment Response in MS: a Prospective Study.
About This Trial
This prospective study combining non conventional MRI techniques, neuropsychological screening tools, and a neurophysiological work-up using a sensitive and validated battery, will evaluate the predictive value of these measures and will explore the changes of the cognitive scores from baseline.
Who May Be Eligible (Plain English)
Who May Qualify:
- active MS, according to the Lublin criteria
- disease duration \< 10 years before initiating or changing a disease-modifying therapies,
- relapse- and steroid-free for at least 1 month before MRI acquisition
- between 18-50 years old
- having given willing to sign a consent form
- with no significant comorbidity other than MS or substance abuse that could interfere with cognitive performances
Who Should NOT Join This Trial:
- progressive forms of MS
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* active MS, according to the Lublin criteria
* disease duration \< 10 years before initiating or changing a disease-modifying therapies,
* relapse- and steroid-free for at least 1 month before MRI acquisition
* between 18-50 years old
* having given informed consent
* with no significant comorbidity other than MS or substance abuse that could interfere with cognitive performances
Exclusion Criteria:
* progressive forms of MS
Treatments Being Tested
OTHER
Multiparametric assessment
neuropsychological assessment, PRO measures, non-conventional MRI metrics
Locations (1)
CHU UCL Namur site Godinne
Yvoir, Namur, Belgium