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RECRUITINGPhase 2INTERVENTIONAL

Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation

Multi-Modality Detection of RCC Recurrence Post Ablation

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This phase II trial studies how well contrast-enhanced ultrasound (CEUS) works for diagnosing patients with renal cell cancer (RCC) that has come back (recurrent) after an ablation. Diagnostic imaging, such as CEUS, may help find and monitor long term renal cell cancer recurrence following cryo or microwave ablation.

Who May Be Eligible (Plain English)

Who May Qualify: - Previously received cryotherapy or microwave therapy of RCC - Has available contrast enhanced (CE)-MRI or CE-CT imaging prior to ablative therapy - Have previously had or are scheduled to have a contrast-enhanced MRI/CT for the monitoring of RCC recurrence within 4 weeks of the CEUS study - Be at least 18 years of age - Be medically stable - If a female of child-bearing age, must have a negative pregnancy test - Have signed willing to sign a consent form to participate in the study Who Should NOT Join This Trial: - Patients who are medically unstable, patients who are seriously or terminally ill, and patients whose clinical course is unpredictable - Patients with known sensitivities to the components of Lumason Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Previously received cryotherapy or microwave therapy of RCC * Has available contrast enhanced (CE)-MRI or CE-CT imaging prior to ablative therapy * Have previously had or are scheduled to have a contrast-enhanced MRI/CT for the monitoring of RCC recurrence within 4 weeks of the CEUS study * Be at least 18 years of age * Be medically stable * If a female of child-bearing age, must have a negative pregnancy test * Have signed Informed Consent to participate in the study Exclusion Criteria: * Patients who are medically unstable, patients who are seriously or terminally ill, and patients whose clinical course is unpredictable * Patients with known sensitivities to the components of Lumason

Treatments Being Tested

DRUG

Sulfur Hexafluoride Lipid Microspheres

Given IV

PROCEDURE

Contrast-Enhanced Ultrasound

Undergo CEUS

PROCEDURE

Computed Tomography

Undergo CT

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

OTHER

Electronic Health Record Review

Review electronic medical record

Locations (1)

Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, United States