RECRUITINGOBSERVATIONAL

Plaque Burden and Ischemia in MINOCA

Coronary Artery Plaque, Perivascular Inflammation and Myocardial Ischemia in Patients With Myocardial Infraction and Non-obstructive Coronary Arteries

About This Trial

The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery disease. The main question it aims to answer are: * Identify coronary artery anatomy, plaque burden, composition and high-risk plaque features by CT coronary angiography in MINOCA * Assess presence, extent and severity of myocardial ischemia in MINOCA Participants will examined by CT coronary angiography and stress \[12N\] NH3 PET-MR.

Who May Be Eligible (Plain English)

Who May Qualify: - Acute chest pain - Elevated troponin - Non-obstructive coronary arteries by coronary angiography Who Should NOT Join This Trial: - Obstructive coronary artery disease - Contraindications against CT coronary angiography or stress \[12N\] NH3 PET-MR - Not able to give willing to sign a consent form Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Acute chest pain * Elevated troponin * Non-obstructive coronary arteries by coronary angiography Exclusion Criteria: * Obstructive coronary artery disease * Contraindications against CT coronary angiography or stress \[12N\] NH3 PET-MR * Not able to give informed consent

Treatments Being Tested

DIAGNOSTIC_TEST

CT coronary angiography and [12N] NH3 PET-MR

Advanced coronary artery plaque analysis, myocardial ischemia and coronary flow reserve

Locations (1)

Department of Clinical Science, University of Bergen

Bergen, Norway