NIVATS Versus IGAVATS: a Pilot Trial Addressing Biopsy Quality in Undetermined Interstitial Lung Diseases

Who May Qualify: - Patient with purported interstitial lung disease - Patient requiring a surgical lung biopsy to reinforce diagnosis according to current recommendations and validated by a multidisciplinary assessment - Minimum age: 18 years Who Should NOT Join This Trial: - Contra-indication for surgery - Uncontrolled oesophageal gastric reflux despite optimal treatment - Thoracic deformation (For example, pectus excavatum/carinatum or major scoliosis) - Risk of pleural adhesion (For example, patient who has already undergone thoracic surgery) - History of abnormal bleeding - Predictable risk of difficult intubation - Body mass index (BMI) \> 30 - Severe cardiovascular comorbidity (For example, instable ischemic cardiomyopathy) - Unable to comply with all trial procedures/visits (For example, language barriers, upcoming move of household to another region, unwillingness to schedule the required followup visits.) - Protected populations according to the French Public Health Code Articles L1121-5,6,8 (For example, pregnant, parturient or lactating women, prisoners, adults under guardianship or otherwise unable to consent.) - Potential interference from another study (The patient is participating in another interventional study, or has done so in the past month, or is affected by an exclusion period stipulated by a previous study.) - Non-beneficiary of the French single-payer national medical insurance system - Lack of signed willing to sign a consent form Always talk to your doctor about whether this trial is right for you.